An antibody-drug conjugate targeting VpreB1 for the treatment of B-cell acute lymphoblastic leukemia

An antibody-drug conjugate targeting VpreB1 for the treatment of B-cell acute lymphoblastic leukemia

Abstract: B-lineage acute lymphoblastic leukemia (B-ALL) therapy is being transformed by therapies targeting antigens such as CD19, CD20, and CD22 on the surface of B-ALL cells. Moreover, having therapies targeting these different B-ALL antigens has helped address challenges associated with both int...

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Main Authors: Peter M. Gordon, Robin L. Williams, Jason Ostergaard, Keegan C. Lee, Hannah N. Bui, Joseph M. Muretta, Bridget S. Wilson, Thomas Beder, Claudia D. Baldus, Luke Lambert, Benjamin E. Deonovic, Timothy Singleton, Sarah K. Tasian, Stuart S. Winter
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Blood Neoplasia
Online Access:http://www.sciencedirect.com/science/article/pii/S295032802500055X
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