“May-Thurner syndrome as an underlying cause of unilateral left-sided deep vein thrombosis in a young healthy female: A case report”

May-Thurner syndrome (MTS), iliac vein compression syndrome, also called Cockett syndrome, is a vascular disease caused by the compression of the left common iliac vein (LCIV) by the right common iliac artery (RCIA) against the lumbar vertebrae. This anatomical defect can lead to venous stasis espec...

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Main Authors: Khaled Sawafta, Fadi Yousef, Hani Abu Hijleh, Wasef Abdat, Yousef Samara, Tasbeeh Al-Kharraz
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Radiology Case Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S193004332401402X
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author Khaled Sawafta
Fadi Yousef
Hani Abu Hijleh
Wasef Abdat
Yousef Samara
Tasbeeh Al-Kharraz
author_facet Khaled Sawafta
Fadi Yousef
Hani Abu Hijleh
Wasef Abdat
Yousef Samara
Tasbeeh Al-Kharraz
author_sort Khaled Sawafta
collection DOAJ
description May-Thurner syndrome (MTS), iliac vein compression syndrome, also called Cockett syndrome, is a vascular disease caused by the compression of the left common iliac vein (LCIV) by the right common iliac artery (RCIA) against the lumbar vertebrae. This anatomical defect can lead to venous stasis especially in the left lower limb, and this increases the risk of deep venous thrombosis (DVT). Because routine screening is not standard practice, MTS frequently remains asymptomatic, and its prevalence is probably underestimated. Our case report presents 33 year old women with no thrombotic condition history who complained from a left leg swelling, pain, and stiffness over 5 days. Computed tomography angiography (CTA) confirmed a diagnosis of MTS, and Doppler ultrasonography confirmed extensive DVT in the left lower limb. After receiving conservative treatment with enoxaparin, the patient switched to apixaban therapy. The significance of identifying MTS as a possible cause of unilateral left-sided DVT is highlighted by this case, especially in young, otherwise healthy women. Recurrent DVT and chronic venous insufficiency are among the complications that can be prevented by early detection with imaging and anticoagulation treatment. Patients with atypical DVT presentations may benefit from earlier diagnosis and treatment made possible by greater knowledge of MTS.
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spelling doaj-art-da3d3a6ee19d44688489e1344e04d6e02025-01-18T05:04:13ZengElsevierRadiology Case Reports1930-04332025-03-0120317401744“May-Thurner syndrome as an underlying cause of unilateral left-sided deep vein thrombosis in a young healthy female: A case report”Khaled Sawafta0Fadi Yousef1Hani Abu Hijleh2Wasef Abdat3Yousef Samara4Tasbeeh Al-Kharraz5Department of Medicine, An Najah National University, Nablus, Palestine; Corresponding author.Department of Medicine, An Najah National University, Nablus, PalestineDepartment of Medicine, An Najah National University, Nablus, PalestineDepartment of Medicine, An Najah National University, Nablus, PalestineDepartment of Medicine, An Najah National University, Nablus, PalestineDepartment of Radiology, Rafidia Surgical Hospital, Nablus, PalestineMay-Thurner syndrome (MTS), iliac vein compression syndrome, also called Cockett syndrome, is a vascular disease caused by the compression of the left common iliac vein (LCIV) by the right common iliac artery (RCIA) against the lumbar vertebrae. This anatomical defect can lead to venous stasis especially in the left lower limb, and this increases the risk of deep venous thrombosis (DVT). Because routine screening is not standard practice, MTS frequently remains asymptomatic, and its prevalence is probably underestimated. Our case report presents 33 year old women with no thrombotic condition history who complained from a left leg swelling, pain, and stiffness over 5 days. Computed tomography angiography (CTA) confirmed a diagnosis of MTS, and Doppler ultrasonography confirmed extensive DVT in the left lower limb. After receiving conservative treatment with enoxaparin, the patient switched to apixaban therapy. The significance of identifying MTS as a possible cause of unilateral left-sided DVT is highlighted by this case, especially in young, otherwise healthy women. Recurrent DVT and chronic venous insufficiency are among the complications that can be prevented by early detection with imaging and anticoagulation treatment. Patients with atypical DVT presentations may benefit from earlier diagnosis and treatment made possible by greater knowledge of MTS.http://www.sciencedirect.com/science/article/pii/S193004332401402XMay-Thurner syndromeDeep vein thrombosisIliac vein compression syndromeComputed tomography angiographyAnticoagulation therapyMiscarriages
spellingShingle Khaled Sawafta
Fadi Yousef
Hani Abu Hijleh
Wasef Abdat
Yousef Samara
Tasbeeh Al-Kharraz
“May-Thurner syndrome as an underlying cause of unilateral left-sided deep vein thrombosis in a young healthy female: A case report”
Radiology Case Reports
May-Thurner syndrome
Deep vein thrombosis
Iliac vein compression syndrome
Computed tomography angiography
Anticoagulation therapy
Miscarriages
title “May-Thurner syndrome as an underlying cause of unilateral left-sided deep vein thrombosis in a young healthy female: A case report”
title_full “May-Thurner syndrome as an underlying cause of unilateral left-sided deep vein thrombosis in a young healthy female: A case report”
title_fullStr “May-Thurner syndrome as an underlying cause of unilateral left-sided deep vein thrombosis in a young healthy female: A case report”
title_full_unstemmed “May-Thurner syndrome as an underlying cause of unilateral left-sided deep vein thrombosis in a young healthy female: A case report”
title_short “May-Thurner syndrome as an underlying cause of unilateral left-sided deep vein thrombosis in a young healthy female: A case report”
title_sort may thurner syndrome as an underlying cause of unilateral left sided deep vein thrombosis in a young healthy female a case report
topic May-Thurner syndrome
Deep vein thrombosis
Iliac vein compression syndrome
Computed tomography angiography
Anticoagulation therapy
Miscarriages
url http://www.sciencedirect.com/science/article/pii/S193004332401402X
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