Orbital Solitary Fibrous Tumor: Four Case Reports—Clinical and Histopathological Features

Purpose. To retrospectively describe the clinical characteristics, management, and outcomes of four cases of orbital solitary fibrous tumor (SFT). In one patient, we present an ultrasonic aspirator system for tumor removal. Methods. Four patients with orbital SFT were selected: one patient with orbi...

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Main Authors: Carmen Navarro-Perea, Cristina Calleja-García, Álvaro Bengoa-González, María-C. Garrido, Enrique Mencía-Gutiérrez, Silvia Pérez-Trigo
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Ophthalmological Medicine
Online Access:http://dx.doi.org/10.1155/2021/5822859
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author Carmen Navarro-Perea
Cristina Calleja-García
Álvaro Bengoa-González
María-C. Garrido
Enrique Mencía-Gutiérrez
Silvia Pérez-Trigo
author_facet Carmen Navarro-Perea
Cristina Calleja-García
Álvaro Bengoa-González
María-C. Garrido
Enrique Mencía-Gutiérrez
Silvia Pérez-Trigo
author_sort Carmen Navarro-Perea
collection DOAJ
description Purpose. To retrospectively describe the clinical characteristics, management, and outcomes of four cases of orbital solitary fibrous tumor (SFT). In one patient, we present an ultrasonic aspirator system for tumor removal. Methods. Four patients with orbital SFT were selected: one patient with orbital SFT, another patient with frontal and ethmoidal SFT and orbital affectation with high rates of recurrence, the third patient with frontal lobe SFT and orbital invasion with multiple recurrences, and the fourth case with a history of craniopharyngioma surgery and SFT located on the orbital apex. Results. All cases showed proptosis, eye movement restriction, and, in three cases, visual acuity alteration. Different treatments were applied: in three cases, excision was performed, one of them with an ultrasonic aspirator system, and in the remaining case, an exenteration was done (in two cases, radiosurgery treatment was also applied). The immunohistochemical study revealed SFT, similar to hemangiopericytomas (HPCs). No recurrence has been observed after surgical treatment. Conclusion. The SFT is a spectrum of different tumors with similar histopathological characteristics. The use of immunohistochemical markers is very helpful in the diagnosis. The main problem of orbital involvement is the risk of damaging important structures adjacent to the tumor during the surgical removal. The ultrasonic aspirator system allows elimination of the tumor without damaging other orbital structures.
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spelling doaj-art-da3b7c3d4f964e33acca9c1df7b98d6d2025-08-20T03:24:25ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302021-01-01202110.1155/2021/58228595822859Orbital Solitary Fibrous Tumor: Four Case Reports—Clinical and Histopathological FeaturesCarmen Navarro-Perea0Cristina Calleja-García1Álvaro Bengoa-González2María-C. Garrido3Enrique Mencía-Gutiérrez4Silvia Pérez-Trigo5Ophthalmology Department, 12 de Octubre Hospital, Complutense University, 28041 Madrid, SpainOphthalmology Department, 12 de Octubre Hospital, Complutense University, 28041 Madrid, SpainOphthalmology Department, 12 de Octubre Hospital, Complutense University, 28041 Madrid, SpainPathology Department, 12 de Octubre Hospital, Complutense University, 28041 Madrid, SpainOphthalmology Department, 12 de Octubre Hospital, Complutense University, 28041 Madrid, SpainOphthalmology Department, 12 de Octubre Hospital, Complutense University, 28041 Madrid, SpainPurpose. To retrospectively describe the clinical characteristics, management, and outcomes of four cases of orbital solitary fibrous tumor (SFT). In one patient, we present an ultrasonic aspirator system for tumor removal. Methods. Four patients with orbital SFT were selected: one patient with orbital SFT, another patient with frontal and ethmoidal SFT and orbital affectation with high rates of recurrence, the third patient with frontal lobe SFT and orbital invasion with multiple recurrences, and the fourth case with a history of craniopharyngioma surgery and SFT located on the orbital apex. Results. All cases showed proptosis, eye movement restriction, and, in three cases, visual acuity alteration. Different treatments were applied: in three cases, excision was performed, one of them with an ultrasonic aspirator system, and in the remaining case, an exenteration was done (in two cases, radiosurgery treatment was also applied). The immunohistochemical study revealed SFT, similar to hemangiopericytomas (HPCs). No recurrence has been observed after surgical treatment. Conclusion. The SFT is a spectrum of different tumors with similar histopathological characteristics. The use of immunohistochemical markers is very helpful in the diagnosis. The main problem of orbital involvement is the risk of damaging important structures adjacent to the tumor during the surgical removal. The ultrasonic aspirator system allows elimination of the tumor without damaging other orbital structures.http://dx.doi.org/10.1155/2021/5822859
spellingShingle Carmen Navarro-Perea
Cristina Calleja-García
Álvaro Bengoa-González
María-C. Garrido
Enrique Mencía-Gutiérrez
Silvia Pérez-Trigo
Orbital Solitary Fibrous Tumor: Four Case Reports—Clinical and Histopathological Features
Case Reports in Ophthalmological Medicine
title Orbital Solitary Fibrous Tumor: Four Case Reports—Clinical and Histopathological Features
title_full Orbital Solitary Fibrous Tumor: Four Case Reports—Clinical and Histopathological Features
title_fullStr Orbital Solitary Fibrous Tumor: Four Case Reports—Clinical and Histopathological Features
title_full_unstemmed Orbital Solitary Fibrous Tumor: Four Case Reports—Clinical and Histopathological Features
title_short Orbital Solitary Fibrous Tumor: Four Case Reports—Clinical and Histopathological Features
title_sort orbital solitary fibrous tumor four case reports clinical and histopathological features
url http://dx.doi.org/10.1155/2021/5822859
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