Extension for Community Healthcare Outcomes-Palliative Care in Africa and Quality of Life, Symptoms, Patient Experience, and Caregiver Distress Among Patients With Cancer

PURPOSEIn this study, we aimed to evaluate the association between the Extension for Community Healthcare Outcomes-Palliative Care (ECHO-PC; ECHO Model–Based comprehensive educational and telementoring intervention) for health care professionals (HCPs) and change in patient-reported quality-of-life...

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Main Authors: Sriram Yennurajalingam, Olaitan Soyannwo, John Weru, Edwina Beryl VND Addo Opare-Lokko, Henriette Burger, Esther Nafulah, Oladayo Aikomo, Adeniyi Adenipekun, Irene Botchway, Mary Ocansey, Jayita Deodhar, Jianliang Dai, Clark R. Andersen, Joseph Anthony Arthur, Aline Rozman de Moraes, Penny A. Stanton, Eduardo Bruera, Suresh Reddy
Format: Article
Language:English
Published: American Society of Clinical Oncology 2025-04-01
Series:JCO Global Oncology
Online Access:https://ascopubs.org/doi/10.1200/GO.24.00236
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author Sriram Yennurajalingam
Olaitan Soyannwo
John Weru
Edwina Beryl VND Addo Opare-Lokko
Henriette Burger
Esther Nafulah
Oladayo Aikomo
Adeniyi Adenipekun
Irene Botchway
Mary Ocansey
Jayita Deodhar
Jianliang Dai
Clark R. Andersen
Joseph Anthony Arthur
Aline Rozman de Moraes
Penny A. Stanton
Eduardo Bruera
Suresh Reddy
author_facet Sriram Yennurajalingam
Olaitan Soyannwo
John Weru
Edwina Beryl VND Addo Opare-Lokko
Henriette Burger
Esther Nafulah
Oladayo Aikomo
Adeniyi Adenipekun
Irene Botchway
Mary Ocansey
Jayita Deodhar
Jianliang Dai
Clark R. Andersen
Joseph Anthony Arthur
Aline Rozman de Moraes
Penny A. Stanton
Eduardo Bruera
Suresh Reddy
author_sort Sriram Yennurajalingam
collection DOAJ
description PURPOSEIn this study, we aimed to evaluate the association between the Extension for Community Healthcare Outcomes-Palliative Care (ECHO-PC; ECHO Model–Based comprehensive educational and telementoring intervention) for health care professionals (HCPs) and change in patient-reported quality-of-life (QOL; Functional Assessment of Cancer Therapy-General [FACT-G]) among patients with advanced cancer. We also examined the association between ECHO-PC and changes in symptom distress (Edmonton Symptom Assessment Scale [ESAS]), patient experience and satisfaction, and caregiver distress scores.METHODSECHO-PC Clinic sessions were conducted twice a month for 1 year by an interdisciplinary team of PC clinicians at the MD Anderson Cancer Center, with participation of experts in PC in sub-Saharan Africa, using standardized curriculum on the basis of PC needs in the region. Study participants included palliative HCPs from ECHO participating programs in Kenya, Nigeria, Ghana, and South Africa. HCPs, their patients, and caregivers were assessed at baseline, 3, 6, 9, and 12 months of the study for QOL (FACT-G), ESAS-Symptom Distress Score (prorated) (SDS), patient experience, satisfaction (FAMCARE-P-16-patient), and caregiver distress (FAMCARE-caregiver).RESULTSTwo hundred seventy patients completed the assessments. Fifty-eight percent was female, the mean age was 56 years, and most common cancer type was breast cancer (24.3%). Multivariate generalized linear mixed model analysis found that ECHO-PC intervention was associated with significant improvement in QOL and symptom distress (FACT-G total score, P = .0433; FACT-G physical well-being, P < .013; FACT-G emotional well-being, P = .0232, and ESAS-SDS, P < .0001). No significant changes were found in patient experience, satisfaction, and caregiver distress scores.CONCLUSIONOur preliminary study found that the ECHO-PC intervention was significantly associated with improvement in patient outcomes including QOL and symptom distress scores. Further studies are needed.
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spelling doaj-art-da376a16139f4ee4a026d53d7460017e2025-08-20T03:06:09ZengAmerican Society of Clinical OncologyJCO Global Oncology2687-89412025-04-011110.1200/GO.24.00236Extension for Community Healthcare Outcomes-Palliative Care in Africa and Quality of Life, Symptoms, Patient Experience, and Caregiver Distress Among Patients With CancerSriram Yennurajalingam0Olaitan Soyannwo1John Weru2Edwina Beryl VND Addo Opare-Lokko3Henriette Burger4Esther Nafulah5Oladayo Aikomo6Adeniyi Adenipekun7Irene Botchway8Mary Ocansey9Jayita Deodhar10Jianliang Dai11Clark R. Andersen12Joseph Anthony Arthur13Aline Rozman de Moraes14Penny A. Stanton15Eduardo Bruera16Suresh Reddy17University of Texas MD Anderson Cancer Center, Houston, TXUniversity College Hospital, Ibadan, NGAga Khan University Hospital, Nairobi, KenyaKorle- Bu Teaching Hospital, Accra, GhanaDivision of Radiation Oncology, Tygerberg Academic Hospital, Parow, South AfricaAga Khan University Hospital, Nairobi, KenyaUniversity College Hospital, Ibadan, NGUniversity College Hospital, Ibadan, NGKorle- Bu Teaching Hospital, Accra, GhanaKorle- Bu Teaching Hospital, Accra, GhanaTata Memorial Hospital, Mumbai, IndiaUniversity of Texas MD Anderson Cancer Center, Houston, TXUniversity of Texas MD Anderson Cancer Center, Houston, TXUniversity of Texas MD Anderson Cancer Center, Houston, TXUniversity of Texas MD Anderson Cancer Center, Houston, TXUniversity of Texas MD Anderson Cancer Center, Houston, TXUniversity of Texas MD Anderson Cancer Center, Houston, TXUniversity of Texas MD Anderson Cancer Center, Houston, TXPURPOSEIn this study, we aimed to evaluate the association between the Extension for Community Healthcare Outcomes-Palliative Care (ECHO-PC; ECHO Model–Based comprehensive educational and telementoring intervention) for health care professionals (HCPs) and change in patient-reported quality-of-life (QOL; Functional Assessment of Cancer Therapy-General [FACT-G]) among patients with advanced cancer. We also examined the association between ECHO-PC and changes in symptom distress (Edmonton Symptom Assessment Scale [ESAS]), patient experience and satisfaction, and caregiver distress scores.METHODSECHO-PC Clinic sessions were conducted twice a month for 1 year by an interdisciplinary team of PC clinicians at the MD Anderson Cancer Center, with participation of experts in PC in sub-Saharan Africa, using standardized curriculum on the basis of PC needs in the region. Study participants included palliative HCPs from ECHO participating programs in Kenya, Nigeria, Ghana, and South Africa. HCPs, their patients, and caregivers were assessed at baseline, 3, 6, 9, and 12 months of the study for QOL (FACT-G), ESAS-Symptom Distress Score (prorated) (SDS), patient experience, satisfaction (FAMCARE-P-16-patient), and caregiver distress (FAMCARE-caregiver).RESULTSTwo hundred seventy patients completed the assessments. Fifty-eight percent was female, the mean age was 56 years, and most common cancer type was breast cancer (24.3%). Multivariate generalized linear mixed model analysis found that ECHO-PC intervention was associated with significant improvement in QOL and symptom distress (FACT-G total score, P = .0433; FACT-G physical well-being, P < .013; FACT-G emotional well-being, P = .0232, and ESAS-SDS, P < .0001). No significant changes were found in patient experience, satisfaction, and caregiver distress scores.CONCLUSIONOur preliminary study found that the ECHO-PC intervention was significantly associated with improvement in patient outcomes including QOL and symptom distress scores. Further studies are needed.https://ascopubs.org/doi/10.1200/GO.24.00236
spellingShingle Sriram Yennurajalingam
Olaitan Soyannwo
John Weru
Edwina Beryl VND Addo Opare-Lokko
Henriette Burger
Esther Nafulah
Oladayo Aikomo
Adeniyi Adenipekun
Irene Botchway
Mary Ocansey
Jayita Deodhar
Jianliang Dai
Clark R. Andersen
Joseph Anthony Arthur
Aline Rozman de Moraes
Penny A. Stanton
Eduardo Bruera
Suresh Reddy
Extension for Community Healthcare Outcomes-Palliative Care in Africa and Quality of Life, Symptoms, Patient Experience, and Caregiver Distress Among Patients With Cancer
JCO Global Oncology
title Extension for Community Healthcare Outcomes-Palliative Care in Africa and Quality of Life, Symptoms, Patient Experience, and Caregiver Distress Among Patients With Cancer
title_full Extension for Community Healthcare Outcomes-Palliative Care in Africa and Quality of Life, Symptoms, Patient Experience, and Caregiver Distress Among Patients With Cancer
title_fullStr Extension for Community Healthcare Outcomes-Palliative Care in Africa and Quality of Life, Symptoms, Patient Experience, and Caregiver Distress Among Patients With Cancer
title_full_unstemmed Extension for Community Healthcare Outcomes-Palliative Care in Africa and Quality of Life, Symptoms, Patient Experience, and Caregiver Distress Among Patients With Cancer
title_short Extension for Community Healthcare Outcomes-Palliative Care in Africa and Quality of Life, Symptoms, Patient Experience, and Caregiver Distress Among Patients With Cancer
title_sort extension for community healthcare outcomes palliative care in africa and quality of life symptoms patient experience and caregiver distress among patients with cancer
url https://ascopubs.org/doi/10.1200/GO.24.00236
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