Antibacterial Activity of Quaternary Ammonium Salt from Diethylaminoethyl Methacrylate
A quaternary ammonium salt was synthesized from diethylaminoethyl methacrylate (DEAEMA) by quaternization with hexadecyl bromide. The resultant compound (Am-h) was characterized by FTIR and NMR spectroscopy. Its bactericidal activity was evaluated by determining minimum inhibitory concentration (MIC...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2010/637549 |
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| _version_ | 1849472886629203968 |
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| author | Makhloufia Mohammed BenaÏssa Tahar Derdour AÏcha Henni Djamel Eddine |
| author_facet | Makhloufia Mohammed BenaÏssa Tahar Derdour AÏcha Henni Djamel Eddine |
| author_sort | Makhloufia Mohammed |
| collection | DOAJ |
| description | A quaternary ammonium salt was synthesized from diethylaminoethyl methacrylate (DEAEMA) by quaternization with hexadecyl bromide. The resultant compound (Am-h) was characterized by FTIR and NMR spectroscopy. Its bactericidal activity was evaluated by determining minimum inhibitory concentration (MIC) values and inhibitory zone diameter against gram positive bacteria (Streptococcus sp.) and gram negative bacteria such as Acenito baumannii, Klebsiella pneumoniae and Proteus sp. respectively. The results showed that the MIC values of the synthesised compound (Am-h) were 2 μg/mL against Acenito baumannii, Klebsiella pneumoniae, Proteus sp. and Streptococcus sp. |
| format | Article |
| id | doaj-art-da2e774e7668464abbbe82fe0031aa37 |
| institution | Kabale University |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-da2e774e7668464abbbe82fe0031aa372025-08-20T03:24:22ZengWileyE-Journal of Chemistry0973-49452090-98102010-01-017S1S61S6610.1155/2010/637549Antibacterial Activity of Quaternary Ammonium Salt from Diethylaminoethyl MethacrylateMakhloufia Mohammed0BenaÏssa Tahar1Derdour AÏcha2Henni Djamel Eddine3Physical Chemistry Studies Laboratory University of Dr. Moulay Tahar, Saïda – 20000, AlgeriaPhysical Chemistry Studies Laboratory University of Dr. Moulay Tahar, Saïda – 20000, AlgeriaApplied Organic Chemistry Laboratory, University of Esénia, Oran-31000, AlgeriaPhytopathology Laboratory, University of Esénia, Oran-31000, AlgeriaA quaternary ammonium salt was synthesized from diethylaminoethyl methacrylate (DEAEMA) by quaternization with hexadecyl bromide. The resultant compound (Am-h) was characterized by FTIR and NMR spectroscopy. Its bactericidal activity was evaluated by determining minimum inhibitory concentration (MIC) values and inhibitory zone diameter against gram positive bacteria (Streptococcus sp.) and gram negative bacteria such as Acenito baumannii, Klebsiella pneumoniae and Proteus sp. respectively. The results showed that the MIC values of the synthesised compound (Am-h) were 2 μg/mL against Acenito baumannii, Klebsiella pneumoniae, Proteus sp. and Streptococcus sp.http://dx.doi.org/10.1155/2010/637549 |
| spellingShingle | Makhloufia Mohammed BenaÏssa Tahar Derdour AÏcha Henni Djamel Eddine Antibacterial Activity of Quaternary Ammonium Salt from Diethylaminoethyl Methacrylate E-Journal of Chemistry |
| title | Antibacterial Activity of Quaternary Ammonium Salt from Diethylaminoethyl Methacrylate |
| title_full | Antibacterial Activity of Quaternary Ammonium Salt from Diethylaminoethyl Methacrylate |
| title_fullStr | Antibacterial Activity of Quaternary Ammonium Salt from Diethylaminoethyl Methacrylate |
| title_full_unstemmed | Antibacterial Activity of Quaternary Ammonium Salt from Diethylaminoethyl Methacrylate |
| title_short | Antibacterial Activity of Quaternary Ammonium Salt from Diethylaminoethyl Methacrylate |
| title_sort | antibacterial activity of quaternary ammonium salt from diethylaminoethyl methacrylate |
| url | http://dx.doi.org/10.1155/2010/637549 |
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