Pretreatment with serine protease inhibitors impairs Leishmania amazonensis survival on macrophages

Pretreatment with serine protease inhibitors impairs Leishmania amazonensis survival on macrophages

Abstract Background Leishmaniases are neglected tropical diseases with great clinical and epidemiological importance. The current chemotherapy available for the treatment of leishmaniasis presents several problems, such as adverse effects, toxicity, long treatment time, and parasite resistance. The...

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Bibliographic Details
Main Authors:	Patrícia de Almeida Machado, Pollyanna Stephanie Gomes, Elaine Soares Coimbra, Herbert Leonel de Matos Guedes
Format:	Article
Language:	English
Published:	BMC 2025-01-01
Series:	Parasites & Vectors
Subjects:	Serine proteases Serine proteases inhibitors Leishmania amazonensis
Online Access:	https://doi.org/10.1186/s13071-024-06630-w
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