The Chalcogen Exchange: The Replacement of Oxygen with Sulfur and Selenium to Boost the Activity of Natural Products

The Chalcogen Exchange: The Replacement of Oxygen with Sulfur and Selenium to Boost the Activity of Natural Products

Antioxidants, such as stilbenes, anthocyanidins, coumarins, tannins and flavonoids, are often based on oxygen-containing redox systems and tend to feature several hydroxyl groups in their chemical structures. From a synthetic perspective, oxygen atoms are prone to bioisosteric replacement with sulfu...

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Bibliographic Details
Main Authors:	Muhammad Jawad Nasim, Wesam Ali, Eufrânio N. da Silva Júnior, Rahman Shah Zaib Saleem, Caroline Gaucher, Jadwiga Handzlik, Silvana Pedatella, Claus Jacob
Format:	Article
Language:	English
Published:	MDPI AG 2025-06-01
Series:	Sci
Subjects:	bioisosteric replacement catalysis hybrid molecules reactive selenium species (RSeS) reactive sulfur species (RSS)
Online Access:	https://www.mdpi.com/2413-4155/7/2/74
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