BNC1 inhibits the development and progression of gastric cancer by regulating the CCL20/JAK-STAT axis

BNC1 inhibits the development and progression of gastric cancer by regulating the CCL20/JAK-STAT axis

The role of basonuclin 1 (BNC1), a zinc finger protein-specific transcription factor, in gastric cancer remains unclear. In this study, BNC1 was downregulated in gastric cancer and functioned as a tumor suppressor. Through integrative analyses of transcriptome sequencing and functional assays, C-C m...

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Bibliographic Details
Main Authors: Lixin Liu, Li Xiong, Hong Peng, Qin Deng, Kang Liu, Shusen Xia
Format: Article
Language:English
Published: PeerJ Inc. 2025-05-01
Series:PeerJ
Subjects:
Gastric Cancer
BNC1
CCL20
JAK2/STAT3
Online Access:https://peerj.com/articles/19477.pdf
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