Indoleamine 2,3-Dioxygenase 1/Aryl Hydrocarbon Receptor Feedback Loop Mediates Anti-inflammation in lipopolysaccharide-stimulated Astrocytes to Dampen Inflammatory Neurotoxicity
Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that regulates cell immune responses in a cell type-specific and ligand-dependent manner. In the central nervous system, astrocytic AhR plays important roles in regulating neuroinflammation by mediating responses to endogenou...
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| Main Authors: | Yu-Ling Gan, Yi-Hsuan Lee |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2025-01-01
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| Series: | Journal of Physiological Investigation |
| Subjects: | |
| Online Access: | https://journals.lww.com/cjop/fulltext/2025/01000/indoleamine_2,3_dioxygenase_1_aryl_hydrocarbon.1.aspx |
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