Indoleamine 2,3-Dioxygenase 1/Aryl Hydrocarbon Receptor Feedback Loop Mediates Anti-inflammation in lipopolysaccharide-stimulated Astrocytes to Dampen Inflammatory Neurotoxicity

Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that regulates cell immune responses in a cell type-specific and ligand-dependent manner. In the central nervous system, astrocytic AhR plays important roles in regulating neuroinflammation by mediating responses to endogenou...

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Bibliographic Details
Main Authors: Yu-Ling Gan, Yi-Hsuan Lee
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:Journal of Physiological Investigation
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Online Access:https://journals.lww.com/cjop/fulltext/2025/01000/indoleamine_2,3_dioxygenase_1_aryl_hydrocarbon.1.aspx
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