Role of Protein Misfolding and Proteostasis Deficiency in Protein Misfolding Diseases and Aging
The misfolding, aggregation, and tissue accumulation of proteins are common events in diverse chronic diseases, known as protein misfolding disorders. Many of these diseases are associated with aging, but the mechanism for this connection is unknown. Recent evidence has shown that the formation and...
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| Main Authors: | Karina Cuanalo-Contreras, Abhisek Mukherjee, Claudio Soto |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2013-01-01
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| Series: | International Journal of Cell Biology |
| Online Access: | http://dx.doi.org/10.1155/2013/638083 |
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