Common cervicovaginal sequencing methods result in discordant molecular diagnoses of bacterial vaginosis and reveal strain level effects of Gardnerella vaginalis

Abstract Bacterial vaginosis (BV) is associated with HIV transmission and pre-term birth, yet the etiology of BV remains unknown. Our analysis addressed that knowledge gap by comparing diagnostic techniques and using Bayesian inference to find species-specific associations with clinical indicators....

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Main Authors: Courtney A. Broedlow, Erik Swanson, Emily M. Cherenack, Chris Basting, Nicholas Fonseca Nogueira, Michael France, Pan Yue, Ashma Chakrawarti, Ana Salazar, Lunnarie Acosta, Patricia Raccamarich, Michael Gale, Jacques Ravel, Lydia A. Fein, Johanna Holm, Maria L. Alcaide, Nichole R. Klatt
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:npj Women's Health
Online Access:https://doi.org/10.1038/s44294-025-00089-5
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