Research progress on the association of bullous pemphigoid with type 2 diabetes mellitus
Bullous pemphigoid (BP) is a common autoimmune bullous disease that predominantly affects the elderly. The incidence of diabetes mellitus (DM) is higher in BP patients than in the general population, and the coexistence of diabetes is considered an adverse prognostic factor in BP patients. A substan...
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| Format: | Article |
| Language: | zho |
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editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology
2025-03-01
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| Series: | Pifu-xingbing zhenliaoxue zazhi |
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| Online Access: | http://pfxbzlx.gdvdc.com/EN/10.3969/j.issn.1674-8468.2025.03.011 |
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| _version_ | 1849700782078689280 |
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| author | ZHANG Ruohan WANG Zhenying |
| author_facet | ZHANG Ruohan WANG Zhenying |
| author_sort | ZHANG Ruohan |
| collection | DOAJ |
| description | Bullous pemphigoid (BP) is a common autoimmune bullous disease that predominantly affects the elderly. The incidence of diabetes mellitus (DM) is higher in BP patients than in the general population, and the coexistence of diabetes is considered an adverse prognostic factor in BP patients. A substantial amount of epidemiological evidence has demonstrated an association between the two conditions. The link between them may be influenced by factors, such as age, immune status, use of medication, and genetic predisposition. However, their causal relationship remains unclear. Early monitoring of blood glucose levels in BP patients and the selection of appropriate treatment strategies are crucial for controlling the disease and improving prognosis. This review describes the relationship between the two conditions from the aspects of epidemiology, pathogenesis, clinical characteristics, and treatment, in order to provide references for further research into their connection and potential mechanisms. |
| format | Article |
| id | doaj-art-d9fa9a8e08184adab38b88e357efc8bf |
| institution | DOAJ |
| issn | 1674-8468 |
| language | zho |
| publishDate | 2025-03-01 |
| publisher | editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology |
| record_format | Article |
| series | Pifu-xingbing zhenliaoxue zazhi |
| spelling | doaj-art-d9fa9a8e08184adab38b88e357efc8bf2025-08-20T03:18:09Zzhoeditoiral office of Journal of Diagnosis and Therapy on Dermato-venereologyPifu-xingbing zhenliaoxue zazhi1674-84682025-03-0132322222710.3969/j.issn.1674-8468.2025.03.011Research progress on the association of bullous pemphigoid with type 2 diabetes mellitusZHANG Ruohan0WANG Zhenying1Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, ChinaShandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, ChinaBullous pemphigoid (BP) is a common autoimmune bullous disease that predominantly affects the elderly. The incidence of diabetes mellitus (DM) is higher in BP patients than in the general population, and the coexistence of diabetes is considered an adverse prognostic factor in BP patients. A substantial amount of epidemiological evidence has demonstrated an association between the two conditions. The link between them may be influenced by factors, such as age, immune status, use of medication, and genetic predisposition. However, their causal relationship remains unclear. Early monitoring of blood glucose levels in BP patients and the selection of appropriate treatment strategies are crucial for controlling the disease and improving prognosis. This review describes the relationship between the two conditions from the aspects of epidemiology, pathogenesis, clinical characteristics, and treatment, in order to provide references for further research into their connection and potential mechanisms.http://pfxbzlx.gdvdc.com/EN/10.3969/j.issn.1674-8468.2025.03.011bullous pemphigoidtype 2 diabetesautoimmune diseasesdipeptidyl peptidase-4 inhibitors |
| spellingShingle | ZHANG Ruohan WANG Zhenying Research progress on the association of bullous pemphigoid with type 2 diabetes mellitus Pifu-xingbing zhenliaoxue zazhi bullous pemphigoid type 2 diabetes autoimmune diseases dipeptidyl peptidase-4 inhibitors |
| title | Research progress on the association of bullous pemphigoid with type 2 diabetes mellitus |
| title_full | Research progress on the association of bullous pemphigoid with type 2 diabetes mellitus |
| title_fullStr | Research progress on the association of bullous pemphigoid with type 2 diabetes mellitus |
| title_full_unstemmed | Research progress on the association of bullous pemphigoid with type 2 diabetes mellitus |
| title_short | Research progress on the association of bullous pemphigoid with type 2 diabetes mellitus |
| title_sort | research progress on the association of bullous pemphigoid with type 2 diabetes mellitus |
| topic | bullous pemphigoid type 2 diabetes autoimmune diseases dipeptidyl peptidase-4 inhibitors |
| url | http://pfxbzlx.gdvdc.com/EN/10.3969/j.issn.1674-8468.2025.03.011 |
| work_keys_str_mv | AT zhangruohan researchprogressontheassociationofbullouspemphigoidwithtype2diabetesmellitus AT wangzhenying researchprogressontheassociationofbullouspemphigoidwithtype2diabetesmellitus |