Flaviviruses induce ER-specific remodelling of protein synthesis.

Flaviviruses induce ER-specific remodelling of protein synthesis.

Flaviviruses orchestrate a unique remodelling of the endoplasmic reticulum (ER) to facilitate translation and processing of their polyprotein, giving rise to virus replication compartments. While the signal recognition particle (SRP)-dependent pathway is the canonical route for ER-targeting of nasce...

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Bibliographic Details
Main Authors: Ho Him Wong, Dorian Richard Kenneth Crudgington, Lewis Siu, Sumana Sanyal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-12-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1012766
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