IQCN disruption causes fertilization failure and male infertility due to manchette assembly defect
Abstract Total fertilization failure (TFF) is an important cause of infertility; however, the genetic basis of TFF caused by male factors remains to be clarified. In this study, whole‐exome sequencing was firstly used to screen for genetic causes of TFF after intracytoplasmic sperm injection (ICSI),...
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| Main Authors: | Jing Dai, Qi Li, Qinwei Zhou, Shen Zhang, Junru Chen, Yize Wang, Jing Guo, Yifan Gu, Fei Gong, Yueqiu Tan, Guangxiu Lu, Wei Zheng, Ge Lin |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2022-11-01
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| Series: | EMBO Molecular Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.15252/emmm.202216501 |
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