Pattern Dynamics of Bacteriemia and Sepsis Pathogens in ICU Patients of Emergency Service

The results of microbiological tests of 2382 blood specimens from 698 patients of three ICUs of the N. V. Sklifosovsky Research Institute of Emergency Service were analysed for a period of 2009 to 2012. No microbial growth was detected in 1160 specimens (48.7%). In the subsequent tests 816 isolates...

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Main Authors: T. V. Chernenkaya, L. A. Borisova, I. V. Aleksandrova, S. I. Rei, O. V. Nikitina, D. A. Kosolapov
Format: Article
Language:Russian
Published: LLC "Publishing House OKI" 2020-05-01
Series:Антибиотики и Химиотерапия
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Online Access:https://www.antibiotics-chemotherapy.ru/jour/article/view/486
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author T. V. Chernenkaya
L. A. Borisova
I. V. Aleksandrova
S. I. Rei
O. V. Nikitina
D. A. Kosolapov
author_facet T. V. Chernenkaya
L. A. Borisova
I. V. Aleksandrova
S. I. Rei
O. V. Nikitina
D. A. Kosolapov
author_sort T. V. Chernenkaya
collection DOAJ
description The results of microbiological tests of 2382 blood specimens from 698 patients of three ICUs of the N. V. Sklifosovsky Research Institute of Emergency Service were analysed for a period of 2009 to 2012. No microbial growth was detected in 1160 specimens (48.7%). In the subsequent tests 816 isolates were used. The quota of grampositive isolates in the pathogen pattern decreased from 51.68 to 35.9% and that of gramnegative isolates increased from 38.26 to 48.1%. The number of the Candida isolates increased from 7.38 to 15.2%. The frequency of the S.aureus and Enterococcus spp. isolates lowered from 26.2 to 13.3% and from 15.4 to 11.5% respectively. The quota of K.pneumoniae isolates and Acinetobacter spp. increased from 8.1 to 18.9% and from 14.1 to 17.4% respectively. Most of the S.aureus isolates were methicillin resistant. All the staphylococcal isolates were susceptible to vancomycin and linezolid. All the strains of K.pneumoniae isolated in 2009-2012 produced extended spectrum beta-lactamases. In 2012 7.8% the K.pneumoniae isolates were resistant to carbapenems. In 2012 25.5% of the Acinetobacter spp. isolates were susceptible to carbapenems and 70.2% were susceptible to cefoperazon/sulbactam.
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series Антибиотики и Химиотерапия
spelling doaj-art-d9cbaf4ac55f432c964aabf37fb173be2025-08-20T02:49:36ZrusLLC "Publishing House OKI"Антибиотики и Химиотерапия0235-29902020-05-01585-61116485Pattern Dynamics of Bacteriemia and Sepsis Pathogens in ICU Patients of Emergency ServiceT. V. Chernenkaya0L. A. Borisova1I. V. Aleksandrova2S. I. Rei3O. V. Nikitina4D. A. Kosolapov5N.V. Sklifosovsky Research Institute of Emergency ServiceN.V. Sklifosovsky Research Institute of Emergency ServiceN.V. Sklifosovsky Research Institute of Emergency ServiceN.V. Sklifosovsky Research Institute of Emergency ServiceN.V. Sklifosovsky Research Institute of Emergency ServiceN.V. Sklifosovsky Research Institute of Emergency ServiceThe results of microbiological tests of 2382 blood specimens from 698 patients of three ICUs of the N. V. Sklifosovsky Research Institute of Emergency Service were analysed for a period of 2009 to 2012. No microbial growth was detected in 1160 specimens (48.7%). In the subsequent tests 816 isolates were used. The quota of grampositive isolates in the pathogen pattern decreased from 51.68 to 35.9% and that of gramnegative isolates increased from 38.26 to 48.1%. The number of the Candida isolates increased from 7.38 to 15.2%. The frequency of the S.aureus and Enterococcus spp. isolates lowered from 26.2 to 13.3% and from 15.4 to 11.5% respectively. The quota of K.pneumoniae isolates and Acinetobacter spp. increased from 8.1 to 18.9% and from 14.1 to 17.4% respectively. Most of the S.aureus isolates were methicillin resistant. All the staphylococcal isolates were susceptible to vancomycin and linezolid. All the strains of K.pneumoniae isolated in 2009-2012 produced extended spectrum beta-lactamases. In 2012 7.8% the K.pneumoniae isolates were resistant to carbapenems. In 2012 25.5% of the Acinetobacter spp. isolates were susceptible to carbapenems and 70.2% were susceptible to cefoperazon/sulbactam.https://www.antibiotics-chemotherapy.ru/jour/article/view/486icubacteriemiapathogensantibiotic resistance
spellingShingle T. V. Chernenkaya
L. A. Borisova
I. V. Aleksandrova
S. I. Rei
O. V. Nikitina
D. A. Kosolapov
Pattern Dynamics of Bacteriemia and Sepsis Pathogens in ICU Patients of Emergency Service
Антибиотики и Химиотерапия
icu
bacteriemia
pathogens
antibiotic resistance
title Pattern Dynamics of Bacteriemia and Sepsis Pathogens in ICU Patients of Emergency Service
title_full Pattern Dynamics of Bacteriemia and Sepsis Pathogens in ICU Patients of Emergency Service
title_fullStr Pattern Dynamics of Bacteriemia and Sepsis Pathogens in ICU Patients of Emergency Service
title_full_unstemmed Pattern Dynamics of Bacteriemia and Sepsis Pathogens in ICU Patients of Emergency Service
title_short Pattern Dynamics of Bacteriemia and Sepsis Pathogens in ICU Patients of Emergency Service
title_sort pattern dynamics of bacteriemia and sepsis pathogens in icu patients of emergency service
topic icu
bacteriemia
pathogens
antibiotic resistance
url https://www.antibiotics-chemotherapy.ru/jour/article/view/486
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AT ivaleksandrova patterndynamicsofbacteriemiaandsepsispathogensinicupatientsofemergencyservice
AT sirei patterndynamicsofbacteriemiaandsepsispathogensinicupatientsofemergencyservice
AT ovnikitina patterndynamicsofbacteriemiaandsepsispathogensinicupatientsofemergencyservice
AT dakosolapov patterndynamicsofbacteriemiaandsepsispathogensinicupatientsofemergencyservice