Expression profiles of Cry1Ab protein and its insecticidal efficacy against the invasive fall armyworm for Chinese domestic GM maize DBN9936

The fall armyworm (FAW) Spodoptera frugiperda, which originated in the Americas, is advancing across China and threatening the nation's maize crops. Currently, one widely used tool for its control is genetically modified (GM) Bacillus thuringiensis (Bt) maize. Sufficient content of Bt protein i...

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Main Authors: Jin-gang LIANG, Dan-dan ZHANG, Dong-yang LI, Sheng-yuan ZHAO, Chen-yao WANG, Yu-tao XIAO, Dong XU, Yi-zhong YANG, Guo-ping LI, Li-li WANG, Yu GAO, Xue-qing YANG, Hai-bin YUAN, Jian LIU, Xiu-jie ZHANG, Kong-ming WU
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2021-03-01
Series:Journal of Integrative Agriculture
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Online Access:http://www.sciencedirect.com/science/article/pii/S209531192063475X
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author Jin-gang LIANG
Dan-dan ZHANG
Dong-yang LI
Sheng-yuan ZHAO
Chen-yao WANG
Yu-tao XIAO
Dong XU
Yi-zhong YANG
Guo-ping LI
Li-li WANG
Yu GAO
Xue-qing YANG
Hai-bin YUAN
Jian LIU
Xiu-jie ZHANG
Kong-ming WU
author_facet Jin-gang LIANG
Dan-dan ZHANG
Dong-yang LI
Sheng-yuan ZHAO
Chen-yao WANG
Yu-tao XIAO
Dong XU
Yi-zhong YANG
Guo-ping LI
Li-li WANG
Yu GAO
Xue-qing YANG
Hai-bin YUAN
Jian LIU
Xiu-jie ZHANG
Kong-ming WU
author_sort Jin-gang LIANG
collection DOAJ
description The fall armyworm (FAW) Spodoptera frugiperda, which originated in the Americas, is advancing across China and threatening the nation's maize crops. Currently, one widely used tool for its control is genetically modified (GM) Bacillus thuringiensis (Bt) maize. Sufficient content of Bt protein in appropriate plant parts is crucial for enhancing resistance against insect pests. In this study, we conducted a systematic investigation of Cry1Ab levels in Chinese domestic GM maize DBN9936, which has recently obtained a biosafety certificate, and evaluated its efficacy against FAW. Quantification of expression levels of Cry1Ab, via ELISA, indicated a spatio-temporal dynamic, with significant variation of mean Cry1Ab, ranging from 0.76 to 8.48 μg g−1 FW with the Cry1Ab protein level ranked as: V6–V8 leaf>R1 leaf>R4 leaf>R1 silk>VT tassel>R4 kernel. Among the nine locations, the Cry1Ab levels in DBN9936 of the Xinxiang, Langfang, and Harbin fields were significantly lower than those from Wuhan and Shenyang, and were slightly, but not significantly lower than those from the other four fields. Furthermore, the artificial diet–Cry1Ab mixture and plant tissue feeding bioassays revealed that DBN9936 has high efficacy against FAW. The insecticidal efficacy of different tissues against FAW larvae reached 34–100% with a descending order of lethality as follows: VT leaf>R4 leaf>R1 husk>R1 silk>VT tassel>R4 kernel. Taken together, our results showed that Bt-Cry1Ab maize DBN9936 has potential as a promising strategy to manage FAW.
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spelling doaj-art-d9c982e3330f4d59aa4d174fcca8c7ef2025-08-20T03:58:54ZengKeAi Communications Co., Ltd.Journal of Integrative Agriculture2095-31192021-03-0120379280310.1016/S2095-3119(20)63475-XExpression profiles of Cry1Ab protein and its insecticidal efficacy against the invasive fall armyworm for Chinese domestic GM maize DBN9936Jin-gang LIANG0Dan-dan ZHANG1Dong-yang LI2Sheng-yuan ZHAO3Chen-yao WANG4Yu-tao XIAO5Dong XU6Yi-zhong YANG7Guo-ping LI8Li-li WANG9Yu GAO10Xue-qing YANG11Hai-bin YUAN12Jian LIU13Xiu-jie ZHANG14Kong-ming WU15Development Center of Science and Technology, Ministry of Agriculture and Rural Affairs, Beijing 100176, P.R.China; LIANG Jin-gang, Tel: +86-10-59198125State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, P.R.ChinaDevelopment Center of Science and Technology, Ministry of Agriculture and Rural Affairs, Beijing 100176, P.R.China; State Key Laboratory of Cotton Biology, Institute of Cotton Research, Chinese Academy of Agricultural Sciences, Anyang 455000, P.R.ChinaState Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, P.R.ChinaDevelopment Center of Science and Technology, Ministry of Agriculture and Rural Affairs, Beijing 100176, P.R.ChinaShenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Genome Analysis Laboratory of the Ministry of Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 518120, P.R.ChinaInstitute of Plant Protection and Soil Science, Hubei Academy of Agricultural Sciences, Wuhan 430064, P.R.ChinaCollege of Horticulture and Plant Protection, Yangzhou University, Yangzhou 225009, P.R.ChinaInstitute of Plant Protection, Henan Academy of Agricultural Sciences, Zhengzhou 450002, P.R.ChinaYantai Academy of Agricultural Sciences, Yantai 265500, P.R.ChinaState Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, P.R.ChinaCollege of Plant Protection, Shenyang Agricultural University, Shenyang 110866, P.R.ChinaCollege of Plant Protection, Jilin Agricultural University, Changchun 130118, P.R.ChinaCollege of Agriculture, Northeast Agricultural University, Harbin 150030, P.R.ChinaDevelopment Center of Science and Technology, Ministry of Agriculture and Rural Affairs, Beijing 100176, P.R.China; Correspondence ZHANG Xiu-jie, Tel: +86-10-59198155State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, P.R.China; Correspondence WU Kong-ming, Tel: +86-10-82105551The fall armyworm (FAW) Spodoptera frugiperda, which originated in the Americas, is advancing across China and threatening the nation's maize crops. Currently, one widely used tool for its control is genetically modified (GM) Bacillus thuringiensis (Bt) maize. Sufficient content of Bt protein in appropriate plant parts is crucial for enhancing resistance against insect pests. In this study, we conducted a systematic investigation of Cry1Ab levels in Chinese domestic GM maize DBN9936, which has recently obtained a biosafety certificate, and evaluated its efficacy against FAW. Quantification of expression levels of Cry1Ab, via ELISA, indicated a spatio-temporal dynamic, with significant variation of mean Cry1Ab, ranging from 0.76 to 8.48 μg g−1 FW with the Cry1Ab protein level ranked as: V6–V8 leaf>R1 leaf>R4 leaf>R1 silk>VT tassel>R4 kernel. Among the nine locations, the Cry1Ab levels in DBN9936 of the Xinxiang, Langfang, and Harbin fields were significantly lower than those from Wuhan and Shenyang, and were slightly, but not significantly lower than those from the other four fields. Furthermore, the artificial diet–Cry1Ab mixture and plant tissue feeding bioassays revealed that DBN9936 has high efficacy against FAW. The insecticidal efficacy of different tissues against FAW larvae reached 34–100% with a descending order of lethality as follows: VT leaf>R4 leaf>R1 husk>R1 silk>VT tassel>R4 kernel. Taken together, our results showed that Bt-Cry1Ab maize DBN9936 has potential as a promising strategy to manage FAW.http://www.sciencedirect.com/science/article/pii/S209531192063475Xfall armywormgenetically modified maizeDBN9936Cry1Ab expressioncontrol efficacy
spellingShingle Jin-gang LIANG
Dan-dan ZHANG
Dong-yang LI
Sheng-yuan ZHAO
Chen-yao WANG
Yu-tao XIAO
Dong XU
Yi-zhong YANG
Guo-ping LI
Li-li WANG
Yu GAO
Xue-qing YANG
Hai-bin YUAN
Jian LIU
Xiu-jie ZHANG
Kong-ming WU
Expression profiles of Cry1Ab protein and its insecticidal efficacy against the invasive fall armyworm for Chinese domestic GM maize DBN9936
Journal of Integrative Agriculture
fall armyworm
genetically modified maize
DBN9936
Cry1Ab expression
control efficacy
title Expression profiles of Cry1Ab protein and its insecticidal efficacy against the invasive fall armyworm for Chinese domestic GM maize DBN9936
title_full Expression profiles of Cry1Ab protein and its insecticidal efficacy against the invasive fall armyworm for Chinese domestic GM maize DBN9936
title_fullStr Expression profiles of Cry1Ab protein and its insecticidal efficacy against the invasive fall armyworm for Chinese domestic GM maize DBN9936
title_full_unstemmed Expression profiles of Cry1Ab protein and its insecticidal efficacy against the invasive fall armyworm for Chinese domestic GM maize DBN9936
title_short Expression profiles of Cry1Ab protein and its insecticidal efficacy against the invasive fall armyworm for Chinese domestic GM maize DBN9936
title_sort expression profiles of cry1ab protein and its insecticidal efficacy against the invasive fall armyworm for chinese domestic gm maize dbn9936
topic fall armyworm
genetically modified maize
DBN9936
Cry1Ab expression
control efficacy
url http://www.sciencedirect.com/science/article/pii/S209531192063475X
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