The Efficacy of Combined Microneedling and Topical Poly-d,l-lactic Acid (Juvelook) Application for Facial Pore Reduction and Skin Texture Improvement
Background:. Enlarged facial pores are a common cosmetic concern influenced by factors such as age, genetics, and increased sebaceous activity. Despite the availability of numerous treatment modalities, results are often variable, and many methods involve significant discomfort or a high number of s...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer
2025-06-01
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| Series: | Plastic and Reconstructive Surgery, Global Open |
| Online Access: | http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000006838 |
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| author | Jovian Wan, MBChB Suk Bae Seo, MD Song Eun Yoon, MD Kyu-Ho Yi, MD, PhD |
| author_facet | Jovian Wan, MBChB Suk Bae Seo, MD Song Eun Yoon, MD Kyu-Ho Yi, MD, PhD |
| author_sort | Jovian Wan, MBChB |
| collection | DOAJ |
| description | Background:. Enlarged facial pores are a common cosmetic concern influenced by factors such as age, genetics, and increased sebaceous activity. Despite the availability of numerous treatment modalities, results are often variable, and many methods involve significant discomfort or a high number of sessions. This case series evaluated the efficacy of combining microneedling with the topical application of poly-d,l-lactic acid (PDLLA, Juvelook, VAIM Inc., Seoul, Korea) in reducing pore size and improving skin texture.
Methods:. Fifteen patients with enlarged facial pores underwent 3 sessions of microneedling with intradermal PDLLA injections spaced 3 weeks apart. Pore size was evaluated using a standardized visual grading scale, and improvements in skin texture were assessed through clinical photography. Patient satisfaction was measured using a 4-point Likert scale.
Results:. All patients demonstrated significant improvements, with pore size scores decreasing from an average of 6 (baseline) to 3 at 12 weeks (P < 0.001) and results maintained through 22 weeks. Skin texture showed noticeable enhancement, and 80% of patients reported high satisfaction levels. Mild transient erythema and edema were observed in some patients, resolving within 48 hours.
Conclusions:. Microneedling combined with topical PDLLA is a minimally invasive, effective treatment for pore reduction and skin texture improvement. Further research, including larger randomized controlled trials and advanced imaging technologies, is warranted to validate these findings and refine the treatment protocol. |
| format | Article |
| id | doaj-art-d9c1e8b925344e46b1c2a79dd516e3cd |
| institution | OA Journals |
| issn | 2169-7574 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Wolters Kluwer |
| record_format | Article |
| series | Plastic and Reconstructive Surgery, Global Open |
| spelling | doaj-art-d9c1e8b925344e46b1c2a79dd516e3cd2025-08-20T02:37:37ZengWolters KluwerPlastic and Reconstructive Surgery, Global Open2169-75742025-06-01136e683810.1097/GOX.0000000000006838202506000-00009The Efficacy of Combined Microneedling and Topical Poly-d,l-lactic Acid (Juvelook) Application for Facial Pore Reduction and Skin Texture ImprovementJovian Wan, MBChB0Suk Bae Seo, MD1Song Eun Yoon, MD2Kyu-Ho Yi, MD, PhD3From the * Medical Research Inc., Wonju, Korea† SeoAhSong Dermatologic Clinic, Seoul, Korea‡ BRANDNEW Aesthetic Surgery Clinic, Seoul, Korea§ Division in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Institute, BK21 FOUR Project, Yonsei University College of Dentistry, Seoul, KoreaBackground:. Enlarged facial pores are a common cosmetic concern influenced by factors such as age, genetics, and increased sebaceous activity. Despite the availability of numerous treatment modalities, results are often variable, and many methods involve significant discomfort or a high number of sessions. This case series evaluated the efficacy of combining microneedling with the topical application of poly-d,l-lactic acid (PDLLA, Juvelook, VAIM Inc., Seoul, Korea) in reducing pore size and improving skin texture. Methods:. Fifteen patients with enlarged facial pores underwent 3 sessions of microneedling with intradermal PDLLA injections spaced 3 weeks apart. Pore size was evaluated using a standardized visual grading scale, and improvements in skin texture were assessed through clinical photography. Patient satisfaction was measured using a 4-point Likert scale. Results:. All patients demonstrated significant improvements, with pore size scores decreasing from an average of 6 (baseline) to 3 at 12 weeks (P < 0.001) and results maintained through 22 weeks. Skin texture showed noticeable enhancement, and 80% of patients reported high satisfaction levels. Mild transient erythema and edema were observed in some patients, resolving within 48 hours. Conclusions:. Microneedling combined with topical PDLLA is a minimally invasive, effective treatment for pore reduction and skin texture improvement. Further research, including larger randomized controlled trials and advanced imaging technologies, is warranted to validate these findings and refine the treatment protocol.http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000006838 |
| spellingShingle | Jovian Wan, MBChB Suk Bae Seo, MD Song Eun Yoon, MD Kyu-Ho Yi, MD, PhD The Efficacy of Combined Microneedling and Topical Poly-d,l-lactic Acid (Juvelook) Application for Facial Pore Reduction and Skin Texture Improvement Plastic and Reconstructive Surgery, Global Open |
| title | The Efficacy of Combined Microneedling and Topical Poly-d,l-lactic Acid (Juvelook) Application for Facial Pore Reduction and Skin Texture Improvement |
| title_full | The Efficacy of Combined Microneedling and Topical Poly-d,l-lactic Acid (Juvelook) Application for Facial Pore Reduction and Skin Texture Improvement |
| title_fullStr | The Efficacy of Combined Microneedling and Topical Poly-d,l-lactic Acid (Juvelook) Application for Facial Pore Reduction and Skin Texture Improvement |
| title_full_unstemmed | The Efficacy of Combined Microneedling and Topical Poly-d,l-lactic Acid (Juvelook) Application for Facial Pore Reduction and Skin Texture Improvement |
| title_short | The Efficacy of Combined Microneedling and Topical Poly-d,l-lactic Acid (Juvelook) Application for Facial Pore Reduction and Skin Texture Improvement |
| title_sort | efficacy of combined microneedling and topical poly d l lactic acid juvelook application for facial pore reduction and skin texture improvement |
| url | http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000006838 |
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