Iodine promoted one-pot synthesis of flavones
A novel one-pot methodology for the synthesis of flavones starting from simple precursors such as 2′-hydroxyacetophenone and benzaldehyde derivatives in pentan-1-ol (a green solvent), without additives, mediated by iodine and with short reaction times (1 h) is described. A scope of 21 products in yi...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-01-01
|
| Series: | Results in Chemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211715624006647 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832583124138065920 |
|---|---|
| author | Darvin Jesús Torres Ribón Luis Fernando Roa de la Fuente Nancy Romero Ceronio Oswaldo Hernández Abreu Madeleyne Ramos Rivera Jorge R. Juárez Rosalía Torralba Manuel Velasco Ximello Quirino Torres Sauret Cuauhtémoc Alvarado Sánchez |
| author_facet | Darvin Jesús Torres Ribón Luis Fernando Roa de la Fuente Nancy Romero Ceronio Oswaldo Hernández Abreu Madeleyne Ramos Rivera Jorge R. Juárez Rosalía Torralba Manuel Velasco Ximello Quirino Torres Sauret Cuauhtémoc Alvarado Sánchez |
| author_sort | Darvin Jesús Torres Ribón |
| collection | DOAJ |
| description | A novel one-pot methodology for the synthesis of flavones starting from simple precursors such as 2′-hydroxyacetophenone and benzaldehyde derivatives in pentan-1-ol (a green solvent), without additives, mediated by iodine and with short reaction times (1 h) is described. A scope of 21 products in yields ranging from 28 % to 90 % is presented. Results demonstrated that the yield was enhanced by the use of benzaldehyde derivatives with activating substituents on the para-position. |
| format | Article |
| id | doaj-art-d9c06a44255b48faba820c7fea6706a5 |
| institution | Kabale University |
| issn | 2211-7156 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Results in Chemistry |
| spelling | doaj-art-d9c06a44255b48faba820c7fea6706a52025-01-29T05:00:44ZengElsevierResults in Chemistry2211-71562025-01-0113101968Iodine promoted one-pot synthesis of flavonesDarvin Jesús Torres Ribón0Luis Fernando Roa de la Fuente1Nancy Romero Ceronio2Oswaldo Hernández Abreu3Madeleyne Ramos Rivera4Jorge R. Juárez5Rosalía Torralba6Manuel Velasco Ximello7Quirino Torres Sauret8Cuauhtémoc Alvarado Sánchez9Laboratorio de Química Orgánica, Centro de Investigación en Ciencia y Tecnología Aplicada de Tabasco (CICTAT), División Académica de Ciencias Básicas, Universidad Juárez Autónoma de Tabasco, Carretera Cunduacán-Jalpa Km 1, Col. La Esperanza, 86690 Cunduacán, Tabasco, MexicoLaboratorio de Química Orgánica, Centro de Investigación en Ciencia y Tecnología Aplicada de Tabasco (CICTAT), División Académica de Ciencias Básicas, Universidad Juárez Autónoma de Tabasco, Carretera Cunduacán-Jalpa Km 1, Col. La Esperanza, 86690 Cunduacán, Tabasco, MexicoLaboratorio de Química Orgánica, Centro de Investigación en Ciencia y Tecnología Aplicada de Tabasco (CICTAT), División Académica de Ciencias Básicas, Universidad Juárez Autónoma de Tabasco, Carretera Cunduacán-Jalpa Km 1, Col. La Esperanza, 86690 Cunduacán, Tabasco, MexicoLaboratorio de Química Orgánica, Centro de Investigación en Ciencia y Tecnología Aplicada de Tabasco (CICTAT), División Académica de Ciencias Básicas, Universidad Juárez Autónoma de Tabasco, Carretera Cunduacán-Jalpa Km 1, Col. La Esperanza, 86690 Cunduacán, Tabasco, MexicoLaboratorio de Química Orgánica, Centro de Investigación en Ciencia y Tecnología Aplicada de Tabasco (CICTAT), División Académica de Ciencias Básicas, Universidad Juárez Autónoma de Tabasco, Carretera Cunduacán-Jalpa Km 1, Col. La Esperanza, 86690 Cunduacán, Tabasco, MexicoCentro de Ciencias Químicas, Instituto de Ciencias, Benemérita Universidad Autónoma de Puebla, Edificio IC8, Complejo de Ciencias, C.U., 72750 Puebla, Puebla, MexicoComplejo Regional Mixteca, Campus Izúcar de Matamoros 141, Benemérita Universidad Autónoma de Puebla, Carr. Atlixco-Izúcar de Matamoros 141, San Martín Alchichica, Izúcar de Matamoros 74750, Puebla, MexicoComplejo Regional Mixteca, Campus Izúcar de Matamoros 141, Benemérita Universidad Autónoma de Puebla, Carr. Atlixco-Izúcar de Matamoros 141, San Martín Alchichica, Izúcar de Matamoros 74750, Puebla, MexicoLaboratorio de Química Orgánica, Centro de Investigación en Ciencia y Tecnología Aplicada de Tabasco (CICTAT), División Académica de Ciencias Básicas, Universidad Juárez Autónoma de Tabasco, Carretera Cunduacán-Jalpa Km 1, Col. La Esperanza, 86690 Cunduacán, Tabasco, MexicoLaboratorio de Química Orgánica, Centro de Investigación en Ciencia y Tecnología Aplicada de Tabasco (CICTAT), División Académica de Ciencias Básicas, Universidad Juárez Autónoma de Tabasco, Carretera Cunduacán-Jalpa Km 1, Col. La Esperanza, 86690 Cunduacán, Tabasco, Mexico; Corresponding author.A novel one-pot methodology for the synthesis of flavones starting from simple precursors such as 2′-hydroxyacetophenone and benzaldehyde derivatives in pentan-1-ol (a green solvent), without additives, mediated by iodine and with short reaction times (1 h) is described. A scope of 21 products in yields ranging from 28 % to 90 % is presented. Results demonstrated that the yield was enhanced by the use of benzaldehyde derivatives with activating substituents on the para-position.http://www.sciencedirect.com/science/article/pii/S2211715624006647FlavonesOne-pot synthesisIodine-promoted synthesis |
| spellingShingle | Darvin Jesús Torres Ribón Luis Fernando Roa de la Fuente Nancy Romero Ceronio Oswaldo Hernández Abreu Madeleyne Ramos Rivera Jorge R. Juárez Rosalía Torralba Manuel Velasco Ximello Quirino Torres Sauret Cuauhtémoc Alvarado Sánchez Iodine promoted one-pot synthesis of flavones Results in Chemistry Flavones One-pot synthesis Iodine-promoted synthesis |
| title | Iodine promoted one-pot synthesis of flavones |
| title_full | Iodine promoted one-pot synthesis of flavones |
| title_fullStr | Iodine promoted one-pot synthesis of flavones |
| title_full_unstemmed | Iodine promoted one-pot synthesis of flavones |
| title_short | Iodine promoted one-pot synthesis of flavones |
| title_sort | iodine promoted one pot synthesis of flavones |
| topic | Flavones One-pot synthesis Iodine-promoted synthesis |
| url | http://www.sciencedirect.com/science/article/pii/S2211715624006647 |
| work_keys_str_mv | AT darvinjesustorresribon iodinepromotedonepotsynthesisofflavones AT luisfernandoroadelafuente iodinepromotedonepotsynthesisofflavones AT nancyromeroceronio iodinepromotedonepotsynthesisofflavones AT oswaldohernandezabreu iodinepromotedonepotsynthesisofflavones AT madeleyneramosrivera iodinepromotedonepotsynthesisofflavones AT jorgerjuarez iodinepromotedonepotsynthesisofflavones AT rosaliatorralba iodinepromotedonepotsynthesisofflavones AT manuelvelascoximello iodinepromotedonepotsynthesisofflavones AT quirinotorressauret iodinepromotedonepotsynthesisofflavones AT cuauhtemocalvaradosanchez iodinepromotedonepotsynthesisofflavones |