Involvement of GABA/BDZ receptors in the anticonvulsant effects of dihydrosanguinarine from Bocconia arborea S. Watson

Involvement of GABA/BDZ receptors in the anticonvulsant effects of dihydrosanguinarine from Bocconia arborea S. Watson

Bocconia arborea S. Watson (B. arborea) belongs to the Papaveraceae family and is used in folk medicine because of its depressant effect on the central nervous system. However, its benefits on cerebral paroxysmal activity as an anticonvulsant treatment remain unknown. This study aimed to evaluate th...

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Bibliographic Details
Main Authors: José David González-Gómez, Samuel Estrada-Soto, Emmanuel Gaona-Tovar, María Eva González-Trujano, Benjamín Villasana-Salazar, Hugo Fernando Narváez-González, David Martínez-Vargas
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Heliyon
Subjects:
Alkaloids
Bocconia arborea
Dihydrosanguinarine
Electrocorticogram
Seizures
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844025010825
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