Unfavorable Tumor Responses to Immunotherapy in the Liver: Lessons Learned from Clinical and Preclinical Studies

Unfavorable Tumor Responses to Immunotherapy in the Liver: Lessons Learned from Clinical and Preclinical Studies

Objective: Immunotherapy with immune checkpoint inhibitors (ICIs) has become a standard of care for many malignancies. The tumor microenvironment (TME) varies across different organs and affects tumor initiation, progression, and treatment outcomes. Organ-specific differential responses to ICIs have...

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Bibliographic Details
Main Authors: Li-Chun Lu, Gen-Sheng Feng, Chih-Hung Hsu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-04-01
Series:Journal of Cancer Research and Practice
Subjects:
cancer
immunosuppression
liver
tumor microenvironment
immune checkpoint inhibitor
Online Access:https://journals.lww.com/10.4103/ejcrp.eJCRP-D-22-00033
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