Low IL-6, IL-10, and TNF-α and High IL-13 Cytokine Levels Are Associated with Severe Hepatic Fibrosis in Schistosoma mansoni Chronically Exposed Individuals

Several studies have attributed the etiopathogenesis of chronic Schistosoma mansoni related hepatic fibrosis to unregulated immune responses against trapped parasite ova in the host. However, there is limited data on immune profiles associated with varying degrees of the disease in a population unde...

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Bibliographic Details
Main Authors: Mable M. Mutengo, Takafira Mduluza, Paul Kelly, James C. L. Mwansa, Geoffrey Kwenda, Patrick Musonda, James Chipeta
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Journal of Parasitology Research
Online Access:http://dx.doi.org/10.1155/2018/9754060
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