Seroprevalence of mumps, varicella and rubella antibodies in children 1-16 years of age in eastern Turkey

In this study, seroprevalence of mumps, varicella and rubella was investigated in 803 unvaccinated children in eastern Turkey whose ages ranged between 1 and 16 years. Mumps IgG, varicella IgG and rubella IgG antibody levels in all children were studied by enzyme-linked immunosorbent assay (E...

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Main Authors: Metin Kaya Gürgöze, Erdal Yilmaz, Ahmet Gödekmerdan, Zehra Akça, Yaşar Doğan, Saadet Akarsu, A Denizmen Aygün
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 2006-07-01
Series:The Turkish Journal of Pediatrics
Online Access:https://turkjpediatr.org/article/view/2627
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author Metin Kaya Gürgöze
Erdal Yilmaz
Ahmet Gödekmerdan
Zehra Akça
Yaşar Doğan
Saadet Akarsu
A Denizmen Aygün
author_facet Metin Kaya Gürgöze
Erdal Yilmaz
Ahmet Gödekmerdan
Zehra Akça
Yaşar Doğan
Saadet Akarsu
A Denizmen Aygün
author_sort Metin Kaya Gürgöze
collection DOAJ
description In this study, seroprevalence of mumps, varicella and rubella was investigated in 803 unvaccinated children in eastern Turkey whose ages ranged between 1 and 16 years. Mumps IgG, varicella IgG and rubella IgG antibody levels in all children were studied by enzyme-linked immunosorbent assay (ELISA) method. Information regarding socioeconomic characteristics, number of siblings and disease history was gathered for each participant. No significant difference in seropositivity was detected between girls and boys. Seroprevalence of mumps increased with age, with a seropositivity rate of 29.9% in children aged 1-4 years and of 88.8% in those aged 13-16 years. Seroprevalence of varicella increased with age, with a seropositivity rate of 26.8% in children aged 1-4 years and of 90.3% in those aged 13-16 years. Seroprevalence of rubella also increased with age, with a seropositivity rate of 47.3% in the children aged 1-4 years and of 89.2% in those aged 13-16 years. There was a statistically significant increase in the rate of seropositivity with advancing age through the group of 13-16 years old (p < 0.05). In conclusion, in order to avoid mumps, varicella and rubella diseases and their possible complications, children should be vaccinated against these three diseases before the age of two, since seroprevalence increases with age.
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language English
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publisher Hacettepe University Institute of Child Health
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spelling doaj-art-d9b66fc4c0e34f8da3338cb97f5f8cf02025-08-20T03:16:23ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212006-07-01483Seroprevalence of mumps, varicella and rubella antibodies in children 1-16 years of age in eastern TurkeyMetin Kaya Gürgöze0Erdal YilmazAhmet GödekmerdanZehra AkçaYaşar DoğanSaadet AkarsuA Denizmen AygünDepartment of Pediatrics, Firat University Faculty of Medicine, Elaziğ, Turkey. In this study, seroprevalence of mumps, varicella and rubella was investigated in 803 unvaccinated children in eastern Turkey whose ages ranged between 1 and 16 years. Mumps IgG, varicella IgG and rubella IgG antibody levels in all children were studied by enzyme-linked immunosorbent assay (ELISA) method. Information regarding socioeconomic characteristics, number of siblings and disease history was gathered for each participant. No significant difference in seropositivity was detected between girls and boys. Seroprevalence of mumps increased with age, with a seropositivity rate of 29.9% in children aged 1-4 years and of 88.8% in those aged 13-16 years. Seroprevalence of varicella increased with age, with a seropositivity rate of 26.8% in children aged 1-4 years and of 90.3% in those aged 13-16 years. Seroprevalence of rubella also increased with age, with a seropositivity rate of 47.3% in the children aged 1-4 years and of 89.2% in those aged 13-16 years. There was a statistically significant increase in the rate of seropositivity with advancing age through the group of 13-16 years old (p < 0.05). In conclusion, in order to avoid mumps, varicella and rubella diseases and their possible complications, children should be vaccinated against these three diseases before the age of two, since seroprevalence increases with age. https://turkjpediatr.org/article/view/2627
spellingShingle Metin Kaya Gürgöze
Erdal Yilmaz
Ahmet Gödekmerdan
Zehra Akça
Yaşar Doğan
Saadet Akarsu
A Denizmen Aygün
Seroprevalence of mumps, varicella and rubella antibodies in children 1-16 years of age in eastern Turkey
The Turkish Journal of Pediatrics
title Seroprevalence of mumps, varicella and rubella antibodies in children 1-16 years of age in eastern Turkey
title_full Seroprevalence of mumps, varicella and rubella antibodies in children 1-16 years of age in eastern Turkey
title_fullStr Seroprevalence of mumps, varicella and rubella antibodies in children 1-16 years of age in eastern Turkey
title_full_unstemmed Seroprevalence of mumps, varicella and rubella antibodies in children 1-16 years of age in eastern Turkey
title_short Seroprevalence of mumps, varicella and rubella antibodies in children 1-16 years of age in eastern Turkey
title_sort seroprevalence of mumps varicella and rubella antibodies in children 1 16 years of age in eastern turkey
url https://turkjpediatr.org/article/view/2627
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