Secondary Metabolites of Marine Microorganisms. III. Marine Fungi - a Source of Bioactive Products
Marine-derived fungi are a rich source of structurally diverse bioactive secondary metabolites which might be useful for drug design. Up to date, a lot of structurally and pharmacologically novel and interesting bioactive secondary metabolites have been isolated from marine-derived fungi. Some of th...
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| Format: | Article |
| Language: | Russian |
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LLC "Publishing House OKI"
2020-05-01
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| Series: | Антибиотики и Химиотерапия |
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| Online Access: | https://www.antibiotics-chemotherapy.ru/jour/article/view/31 |
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| _version_ | 1849389149240426496 |
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| author | T. I. Orlova V. G. Bulgakova A. N. Polin |
| author_facet | T. I. Orlova V. G. Bulgakova A. N. Polin |
| author_sort | T. I. Orlova |
| collection | DOAJ |
| description | Marine-derived fungi are a rich source of structurally diverse bioactive secondary metabolites which might be useful for drug design. Up to date, a lot of structurally and pharmacologically novel and interesting bioactive secondary metabolites have been isolated from marine-derived fungi. Some of them have high toxicity toward cancer cells, however they are also cytotoxic to normal cells. These compounds require structural modifications to decrease the toxicity and increase the antitumor activity. A large number of substances have antibacterial, antifungal, anti-imflammatory and immunomodulatory activities. |
| format | Article |
| id | doaj-art-d9b60ea40fa7433982cef078a83eaf34 |
| institution | Kabale University |
| issn | 0235-2990 |
| language | Russian |
| publishDate | 2020-05-01 |
| publisher | LLC "Publishing House OKI" |
| record_format | Article |
| series | Антибиотики и Химиотерапия |
| spelling | doaj-art-d9b60ea40fa7433982cef078a83eaf342025-08-20T03:42:02ZrusLLC "Publishing House OKI"Антибиотики и Химиотерапия0235-29902020-05-01625-6687630Secondary Metabolites of Marine Microorganisms. III. Marine Fungi - a Source of Bioactive ProductsT. I. Orlova0V. G. Bulgakova1A. N. Polin2M. V. Lomonosov Moscow State UnivercityM. V. Lomonosov Moscow State UnivercityM. V. Lomonosov Moscow State UnivercityMarine-derived fungi are a rich source of structurally diverse bioactive secondary metabolites which might be useful for drug design. Up to date, a lot of structurally and pharmacologically novel and interesting bioactive secondary metabolites have been isolated from marine-derived fungi. Some of them have high toxicity toward cancer cells, however they are also cytotoxic to normal cells. These compounds require structural modifications to decrease the toxicity and increase the antitumor activity. A large number of substances have antibacterial, antifungal, anti-imflammatory and immunomodulatory activities.https://www.antibiotics-chemotherapy.ru/jour/article/view/31marine fungibioactive secondary metaboliteschemical structurecytotoxic activitycancer cell lines |
| spellingShingle | T. I. Orlova V. G. Bulgakova A. N. Polin Secondary Metabolites of Marine Microorganisms. III. Marine Fungi - a Source of Bioactive Products Антибиотики и Химиотерапия marine fungi bioactive secondary metabolites chemical structure cytotoxic activity cancer cell lines |
| title | Secondary Metabolites of Marine Microorganisms. III. Marine Fungi - a Source of Bioactive Products |
| title_full | Secondary Metabolites of Marine Microorganisms. III. Marine Fungi - a Source of Bioactive Products |
| title_fullStr | Secondary Metabolites of Marine Microorganisms. III. Marine Fungi - a Source of Bioactive Products |
| title_full_unstemmed | Secondary Metabolites of Marine Microorganisms. III. Marine Fungi - a Source of Bioactive Products |
| title_short | Secondary Metabolites of Marine Microorganisms. III. Marine Fungi - a Source of Bioactive Products |
| title_sort | secondary metabolites of marine microorganisms iii marine fungi a source of bioactive products |
| topic | marine fungi bioactive secondary metabolites chemical structure cytotoxic activity cancer cell lines |
| url | https://www.antibiotics-chemotherapy.ru/jour/article/view/31 |
| work_keys_str_mv | AT tiorlova secondarymetabolitesofmarinemicroorganismsiiimarinefungiasourceofbioactiveproducts AT vgbulgakova secondarymetabolitesofmarinemicroorganismsiiimarinefungiasourceofbioactiveproducts AT anpolin secondarymetabolitesofmarinemicroorganismsiiimarinefungiasourceofbioactiveproducts |