Severe acute respiratory syndrome by influenza and factors associated with death in older adults: a population study
Introduction: Influenza is characterized by an acute viral infection, which can lead to severe conditions and death, especially in vulnerable populations, such as older adults. Therefore, we sought to analyze cases of severe acute respiratory syndrome (SARS) due to influenza in older adults registe...
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The Journal of Infection in Developing Countries
2023-02-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/16801 |
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| author | Thayna Martins Gonçalves Patrícia Mitsue Saruhashi Shimabukuro Karen Renata Nakamura Hiraki Paulo Henrique Braz-Silva Simone Giannecchini Kelvin Kai-Wang To Monica Taminato Richarlisson Borges de Morais |
| author_facet | Thayna Martins Gonçalves Patrícia Mitsue Saruhashi Shimabukuro Karen Renata Nakamura Hiraki Paulo Henrique Braz-Silva Simone Giannecchini Kelvin Kai-Wang To Monica Taminato Richarlisson Borges de Morais |
| author_sort | Thayna Martins Gonçalves |
| collection | DOAJ |
| description |
Introduction: Influenza is characterized by an acute viral infection, which can lead to severe conditions and death, especially in vulnerable populations, such as older adults. Therefore, we sought to analyze cases of severe acute respiratory syndrome (SARS) due to influenza in older adults registered in Brazil and investigate the factors related to death due to this disease.
Methodology: This is a cross-sectional, population-based study that used secondary data from the Influenza Epidemiological Surveillance Information System (IESIS-Influenza). Older adults aged 60 years and above with laboratory diagnosis of influenza were included.
Results: A total of 3,547 older adults with SARS due to influenza were included, out of which 1,185 cases with death as the outcome were identified. Among older adults with death as the outcome, 87.4% were not vaccinated against influenza. The main risk factors for death were invasive ventilatory support use, intensive care unit admission, brown skin color and dyspnea (p < 0.001).
Conclusions: This study described the profile of older adults with SARS due to influenza in Brazil. Factors associated with death in this population were identified. Moreover, the need to encourage compliance with vaccination among older adults is evident in order to prevent severe cases and unfavorable outcomes related to influenza.
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| format | Article |
| id | doaj-art-d9b1a565a1f54ead92ea48b829b7671d |
| institution | OA Journals |
| issn | 1972-2680 |
| language | English |
| publishDate | 2023-02-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-d9b1a565a1f54ead92ea48b829b7671d2025-08-20T02:27:19ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802023-02-01170210.3855/jidc.16801Severe acute respiratory syndrome by influenza and factors associated with death in older adults: a population studyThayna Martins Gonçalves0Patrícia Mitsue Saruhashi Shimabukuro1Karen Renata Nakamura Hiraki2Paulo Henrique Braz-Silva3Simone Giannecchini4Kelvin Kai-Wang To5Monica Taminato6Richarlisson Borges de Morais7Medical School, Federal University of Uberlandia, Uberlandia, BrazilPaulista Nursing School, Federal University of São Paulo, São Paulo, BrazilInstitute of Biomedical Science, Federal University of Uberlandia, Uberlandia, BrazilLaboratory of Virology (LIM-52), Institute of Tropical Medicine of São Paulo, School of Medicine, University of São Paulo, São Paulo, BrazilDepartment of Experimental and Clinical Medicine, University of Florence, Florence, ItalyState Key Laboratory for Emerging Infectious Diseases, Department of Microbiology, Li KaShing Faculty of Medicine of the University of Hong Kong, Hong Kong, ChinaPaulista Nursing School, Federal University of São Paulo, São Paulo, BrazilPaulista Nursing School, Federal University of São Paulo, São Paulo, Brazil Introduction: Influenza is characterized by an acute viral infection, which can lead to severe conditions and death, especially in vulnerable populations, such as older adults. Therefore, we sought to analyze cases of severe acute respiratory syndrome (SARS) due to influenza in older adults registered in Brazil and investigate the factors related to death due to this disease. Methodology: This is a cross-sectional, population-based study that used secondary data from the Influenza Epidemiological Surveillance Information System (IESIS-Influenza). Older adults aged 60 years and above with laboratory diagnosis of influenza were included. Results: A total of 3,547 older adults with SARS due to influenza were included, out of which 1,185 cases with death as the outcome were identified. Among older adults with death as the outcome, 87.4% were not vaccinated against influenza. The main risk factors for death were invasive ventilatory support use, intensive care unit admission, brown skin color and dyspnea (p < 0.001). Conclusions: This study described the profile of older adults with SARS due to influenza in Brazil. Factors associated with death in this population were identified. Moreover, the need to encourage compliance with vaccination among older adults is evident in order to prevent severe cases and unfavorable outcomes related to influenza. https://jidc.org/index.php/journal/article/view/16801Influenzadeathrisk factorselderlyvaccineinfection |
| spellingShingle | Thayna Martins Gonçalves Patrícia Mitsue Saruhashi Shimabukuro Karen Renata Nakamura Hiraki Paulo Henrique Braz-Silva Simone Giannecchini Kelvin Kai-Wang To Monica Taminato Richarlisson Borges de Morais Severe acute respiratory syndrome by influenza and factors associated with death in older adults: a population study Journal of Infection in Developing Countries Influenza death risk factors elderly vaccine infection |
| title | Severe acute respiratory syndrome by influenza and factors associated with death in older adults: a population study |
| title_full | Severe acute respiratory syndrome by influenza and factors associated with death in older adults: a population study |
| title_fullStr | Severe acute respiratory syndrome by influenza and factors associated with death in older adults: a population study |
| title_full_unstemmed | Severe acute respiratory syndrome by influenza and factors associated with death in older adults: a population study |
| title_short | Severe acute respiratory syndrome by influenza and factors associated with death in older adults: a population study |
| title_sort | severe acute respiratory syndrome by influenza and factors associated with death in older adults a population study |
| topic | Influenza death risk factors elderly vaccine infection |
| url | https://jidc.org/index.php/journal/article/view/16801 |
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