Helicobacter pylori Infection and Hepatobiliary Pathology
Aim. The aim of this review is to analyze and systematize data on the effect of Helicobacter pylori infection on hepatobiliary diseases.Background. Over the past two decades, a growing number of studies have been devoted to the possible involvement of H. pylori infection in the extragastric pathol...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Gastro LLC
2018-09-01
|
| Series: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
| Subjects: | |
| Online Access: | https://www.gastro-j.ru/jour/article/view/248 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1823860161698070528 |
|---|---|
| author | S. V. German I. P. Bobrovnitsky |
| author_facet | S. V. German I. P. Bobrovnitsky |
| author_sort | S. V. German |
| collection | DOAJ |
| description | Aim. The aim of this review is to analyze and systematize data on the effect of Helicobacter pylori infection on hepatobiliary diseases.Background. Over the past two decades, a growing number of studies have been devoted to the possible involvement of H. pylori infection in the extragastric pathology. The presence of the bacterium was detected in many organs and tissues. Its relationship with the development of idiopathic iron-deficiency anemia, B12 deficiency anemia, idiopathic thrombocytopenic purpura is proved. The possible role of the bacterium in the development of hepatobiliary pathology is also discussed. The presence of the bacterium has been revealed in samples taken from the liver tissue, biliary tract, bile and gallstones of patients suffering from hepatobiliary diseases. The involvement of H. pylori in the formation of gallstones is considered possible. Non-alcoholic fatty liver disease (NAFLD) is more often diagnosed in H. pylori infected individuals compared to those not infected. The progression of inflammation in the liver of any nature is noted in the presence of H. pylori infection. Different species of the Helicobacter genus, including H. pylori, are shown to contribute to the development of liver cancer. However, some researchers report data against the involvement of H. pylori in the pathogenesis of various hepatobiliary diseases.Conclusion. The results obtained by the authors cannot be considered unambiguous, thus requiring further research. Given the high prevalence of H. pylori infection and the significant incidence of hepatobiliary pathology, the confirmation of their relationship can be of great epidemiological, preventive and clinical importance. |
| format | Article |
| id | doaj-art-d9a4a51ac068427c9a61bf1c5e12cff9 |
| institution | Kabale University |
| issn | 1382-4376 2658-6673 |
| language | Russian |
| publishDate | 2018-09-01 |
| publisher | Gastro LLC |
| record_format | Article |
| series | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
| spelling | doaj-art-d9a4a51ac068427c9a61bf1c5e12cff92025-02-10T16:14:35ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732018-09-01284152210.22416/1382-4376-2018-28-4-15-22248Helicobacter pylori Infection and Hepatobiliary PathologyS. V. German0I. P. Bobrovnitsky1Centre of Strategic Planning and Management of Medical and Biological Health Risks, Ministry of Healthcare of the Russian FederationCentre of Strategic Planning and Management of Medical and Biological Health Risks, Ministry of Healthcare of the Russian FederationAim. The aim of this review is to analyze and systematize data on the effect of Helicobacter pylori infection on hepatobiliary diseases.Background. Over the past two decades, a growing number of studies have been devoted to the possible involvement of H. pylori infection in the extragastric pathology. The presence of the bacterium was detected in many organs and tissues. Its relationship with the development of idiopathic iron-deficiency anemia, B12 deficiency anemia, idiopathic thrombocytopenic purpura is proved. The possible role of the bacterium in the development of hepatobiliary pathology is also discussed. The presence of the bacterium has been revealed in samples taken from the liver tissue, biliary tract, bile and gallstones of patients suffering from hepatobiliary diseases. The involvement of H. pylori in the formation of gallstones is considered possible. Non-alcoholic fatty liver disease (NAFLD) is more often diagnosed in H. pylori infected individuals compared to those not infected. The progression of inflammation in the liver of any nature is noted in the presence of H. pylori infection. Different species of the Helicobacter genus, including H. pylori, are shown to contribute to the development of liver cancer. However, some researchers report data against the involvement of H. pylori in the pathogenesis of various hepatobiliary diseases.Conclusion. The results obtained by the authors cannot be considered unambiguous, thus requiring further research. Given the high prevalence of H. pylori infection and the significant incidence of hepatobiliary pathology, the confirmation of their relationship can be of great epidemiological, preventive and clinical importance.https://www.gastro-j.ru/jour/article/view/248h. pylori infectioncholelithiasisnon-alcoholic fatty liver diseaseliver cirrhosishepatocellular carcinomacholangiocarcinomacaga |
| spellingShingle | S. V. German I. P. Bobrovnitsky Helicobacter pylori Infection and Hepatobiliary Pathology Российский журнал гастроэнтерологии, гепатологии, колопроктологии h. pylori infection cholelithiasis non-alcoholic fatty liver disease liver cirrhosis hepatocellular carcinoma cholangiocarcinoma caga |
| title | Helicobacter pylori Infection and Hepatobiliary Pathology |
| title_full | Helicobacter pylori Infection and Hepatobiliary Pathology |
| title_fullStr | Helicobacter pylori Infection and Hepatobiliary Pathology |
| title_full_unstemmed | Helicobacter pylori Infection and Hepatobiliary Pathology |
| title_short | Helicobacter pylori Infection and Hepatobiliary Pathology |
| title_sort | helicobacter pylori infection and hepatobiliary pathology |
| topic | h. pylori infection cholelithiasis non-alcoholic fatty liver disease liver cirrhosis hepatocellular carcinoma cholangiocarcinoma caga |
| url | https://www.gastro-j.ru/jour/article/view/248 |
| work_keys_str_mv | AT svgerman helicobacterpyloriinfectionandhepatobiliarypathology AT ipbobrovnitsky helicobacterpyloriinfectionandhepatobiliarypathology |