Serum extracellular vesicle microRNAs as potential biomarkers to predict pembrolizumab response and prognosis in metastatic non-small cell lung cancer patients

Serum extracellular vesicle microRNAs as potential biomarkers to predict pembrolizumab response and prognosis in metastatic non-small cell lung cancer patients

IntroductionCirculating Extracellular Vesicles (cEVs) could represent new non-invasive biomarkers for diagnosis and prognosis in tumors. In the context of Non-Small Cell Lung Cancer (NSCLC) immunotherapy there’s a great need for novel predictive and prognostic biomarkers. This study aims to analyze...

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Bibliographic Details
Main Authors: Daniela Lamorte, Luciana De Luca, Alfredo Tartarone, Stefania Trino, Irene Giulivo, Angelo De Stradis, Maddalena Maietti, Antonella Caivano, Ilaria Laurenzana
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
NSCLC
immunotherapy
liquid biopsy
biomarkers
extracellular vesicles
microRNAs
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1540906/full
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