The effect of low-intensity intradialytic cycling aerobic exercise on cognitive function in patients undergoing continuous hemodialysis
Background. End-stage renal disease (ESRD) patients often experience neurological complications. Mounting evidence suggests cognitive impairment associated with end-stage renal disease is likely related to vascular disruption in the brain, particularly in white matter integrity. Hemodialysis is an i...
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Amaltea Medical Publishing House
2024-09-01
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| Series: | Romanian Journal of Neurology |
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| Online Access: | https://rjn.com.ro/articles/2024.3/RJN_2024_3_Art-05.pdf |
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| author | Andi Sulistyo Saputrana I Putu Alit Pawana Lydia Arfianti Mochammad Thaha Atika Atika |
| author_facet | Andi Sulistyo Saputrana I Putu Alit Pawana Lydia Arfianti Mochammad Thaha Atika Atika |
| author_sort | Andi Sulistyo Saputrana |
| collection | DOAJ |
| description | Background. End-stage renal disease (ESRD) patients often experience neurological complications. Mounting evidence suggests cognitive impairment associated with end-stage renal disease is likely related to vascular disruption in the brain, particularly in white matter integrity. Hemodialysis is an independent risk factor for mild cognitive decline (MCD) of ESRD patients and have serious implications for the quality of life. Intradialysis training is the most ideal choice for hemodialysis patients, because not requiring extra time and the patient is also under the supervision of a doctor when doing the exercises. Method. Eighteen patients with end-stage renal disease (ESRD) were randomized into two groups: a treatment group and a control group, with 9 patients in each group. The treatment group participated in low-intensity aerobic exercise on a cycle ergometer, consisting of two 30-minute sessions per week for 12 weeks. Both groups were instructed to continue their regular hemodialysis and medication regimen. MoCA-INA scores were measured before the intervention and again
after 12 weeks for both groups. Comparisons of MoCA-INA scores were made within each group as well as between the two groups before and after the 12-week intervention. Results. In the treatment group, the MoCA-INA scores showed a significant improvement from baseline to after the intervention (p < 0.001; effect size = 1.88). In contrast, the control group did not exhibit a significant change in MoCA-INA scores (p = 0.468). Additionally, there was a significant difference in the change in MoCA-INA scores between the treatment and control groups after 12 weeks of intervention (p = 0.001). |
| format | Article |
| id | doaj-art-d995fbe232a04e7e9d72ca147308b48e |
| institution | DOAJ |
| issn | 1843-8148 2069-6094 |
| language | English |
| publishDate | 2024-09-01 |
| publisher | Amaltea Medical Publishing House |
| record_format | Article |
| series | Romanian Journal of Neurology |
| spelling | doaj-art-d995fbe232a04e7e9d72ca147308b48e2025-08-20T02:50:01ZengAmaltea Medical Publishing HouseRomanian Journal of Neurology1843-81482069-60942024-09-0123326126610.37897/RJN.2024.3.5The effect of low-intensity intradialytic cycling aerobic exercise on cognitive function in patients undergoing continuous hemodialysisAndi Sulistyo Saputrana0https://orcid.org/0009-0006-9858-3292I Putu Alit Pawana1Lydia Arfianti2Mochammad Thaha3Atika Atika4Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; Department of Physical Medicine and Rehabilitation, Dr. Soetomo General Hospital, Surabaya, Indonesia Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; Sport Injury Rehabilitation Division, Department of Physical Medicine and Rehabilitation, Dr. Soetomo General Hospital, Surabaya, IndonesiaFaculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; Musculoskeletal Rehabilitation Division, Department of Physical Medicine and Rehabilitation, Dr. Soetomo General Hospital, Surabaya, Indonesia Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; Molecular Cardio-Nephrology, Renal Health and Disease, Department of Internal Medicine, Dr. Soetomo General Hospital, Surabaya, Indonesia Department of Public Health and Preventive Medicine, Faculty of Medicine, Airlangga University, Surabaya, IndonesiaBackground. End-stage renal disease (ESRD) patients often experience neurological complications. Mounting evidence suggests cognitive impairment associated with end-stage renal disease is likely related to vascular disruption in the brain, particularly in white matter integrity. Hemodialysis is an independent risk factor for mild cognitive decline (MCD) of ESRD patients and have serious implications for the quality of life. Intradialysis training is the most ideal choice for hemodialysis patients, because not requiring extra time and the patient is also under the supervision of a doctor when doing the exercises. Method. Eighteen patients with end-stage renal disease (ESRD) were randomized into two groups: a treatment group and a control group, with 9 patients in each group. The treatment group participated in low-intensity aerobic exercise on a cycle ergometer, consisting of two 30-minute sessions per week for 12 weeks. Both groups were instructed to continue their regular hemodialysis and medication regimen. MoCA-INA scores were measured before the intervention and again after 12 weeks for both groups. Comparisons of MoCA-INA scores were made within each group as well as between the two groups before and after the 12-week intervention. Results. In the treatment group, the MoCA-INA scores showed a significant improvement from baseline to after the intervention (p < 0.001; effect size = 1.88). In contrast, the control group did not exhibit a significant change in MoCA-INA scores (p = 0.468). Additionally, there was a significant difference in the change in MoCA-INA scores between the treatment and control groups after 12 weeks of intervention (p = 0.001).https://rjn.com.ro/articles/2024.3/RJN_2024_3_Art-05.pdfend-stage renal diseasecognitive functionintradialysis exercise |
| spellingShingle | Andi Sulistyo Saputrana I Putu Alit Pawana Lydia Arfianti Mochammad Thaha Atika Atika The effect of low-intensity intradialytic cycling aerobic exercise on cognitive function in patients undergoing continuous hemodialysis Romanian Journal of Neurology end-stage renal disease cognitive function intradialysis exercise |
| title | The effect of low-intensity intradialytic cycling aerobic exercise on cognitive function in patients undergoing continuous hemodialysis |
| title_full | The effect of low-intensity intradialytic cycling aerobic exercise on cognitive function in patients undergoing continuous hemodialysis |
| title_fullStr | The effect of low-intensity intradialytic cycling aerobic exercise on cognitive function in patients undergoing continuous hemodialysis |
| title_full_unstemmed | The effect of low-intensity intradialytic cycling aerobic exercise on cognitive function in patients undergoing continuous hemodialysis |
| title_short | The effect of low-intensity intradialytic cycling aerobic exercise on cognitive function in patients undergoing continuous hemodialysis |
| title_sort | effect of low intensity intradialytic cycling aerobic exercise on cognitive function in patients undergoing continuous hemodialysis |
| topic | end-stage renal disease cognitive function intradialysis exercise |
| url | https://rjn.com.ro/articles/2024.3/RJN_2024_3_Art-05.pdf |
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