Prospects for neuroretinoprotective therapy of glaucoma

The results of present-day research into the pathogenesis of glaucoma as a neurodegenerative disease, leave no doubt that neuroprotective therapy of the condition is needed. It has been proven that achieving the target intraocular pressure does not always lead to the stabilization of the glaucoma pr...

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Main Authors: A. E. Aprelev, E. O. Sukmanyu
Format: Article
Language:Russian
Published: Real Time Ltd 2023-12-01
Series:Российский офтальмологический журнал
Subjects:
Online Access:https://roj.igb.ru/jour/article/view/1369
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author A. E. Aprelev
E. O. Sukmanyu
author_facet A. E. Aprelev
E. O. Sukmanyu
author_sort A. E. Aprelev
collection DOAJ
description The results of present-day research into the pathogenesis of glaucoma as a neurodegenerative disease, leave no doubt that neuroprotective therapy of the condition is needed. It has been proven that achieving the target intraocular pressure does not always lead to the stabilization of the glaucoma process, as evidenced by a further decrease in visual functions and the death of retinal ganglion cells. Currently, research is focused on finding new drugs that can slow down the damage to the nerve fibers of the optic nerve and prevent apoptotic neuronal death. This literature review presents the results of recent experimental and clinical studies of the most promising neuroprotective drugs.
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institution Kabale University
issn 2072-0076
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publishDate 2023-12-01
publisher Real Time Ltd
record_format Article
series Российский офтальмологический журнал
spelling doaj-art-d97b8ae9674440cb9052f4b2e48664482025-08-20T03:59:17ZrusReal Time LtdРоссийский офтальмологический журнал2072-00762587-57602023-12-0116414715110.21516/2072-0076-2023-16-4-147-151653Prospects for neuroretinoprotective therapy of glaucomaA. E. Aprelev0E. O. Sukmanyu1Orenburg State Medical UniversityOrenburg State Medical UniversityThe results of present-day research into the pathogenesis of glaucoma as a neurodegenerative disease, leave no doubt that neuroprotective therapy of the condition is needed. It has been proven that achieving the target intraocular pressure does not always lead to the stabilization of the glaucoma process, as evidenced by a further decrease in visual functions and the death of retinal ganglion cells. Currently, research is focused on finding new drugs that can slow down the damage to the nerve fibers of the optic nerve and prevent apoptotic neuronal death. This literature review presents the results of recent experimental and clinical studies of the most promising neuroprotective drugs.https://roj.igb.ru/jour/article/view/1369glaucomaneuroprotectionglaucomatous optic neuropathy
spellingShingle A. E. Aprelev
E. O. Sukmanyu
Prospects for neuroretinoprotective therapy of glaucoma
Российский офтальмологический журнал
glaucoma
neuroprotection
glaucomatous optic neuropathy
title Prospects for neuroretinoprotective therapy of glaucoma
title_full Prospects for neuroretinoprotective therapy of glaucoma
title_fullStr Prospects for neuroretinoprotective therapy of glaucoma
title_full_unstemmed Prospects for neuroretinoprotective therapy of glaucoma
title_short Prospects for neuroretinoprotective therapy of glaucoma
title_sort prospects for neuroretinoprotective therapy of glaucoma
topic glaucoma
neuroprotection
glaucomatous optic neuropathy
url https://roj.igb.ru/jour/article/view/1369
work_keys_str_mv AT aeaprelev prospectsforneuroretinoprotectivetherapyofglaucoma
AT eosukmanyu prospectsforneuroretinoprotectivetherapyofglaucoma