LACTOFERIN IN THE PROBLEM OF ANTI-INFECTIOUS PROTECTION OF BABIES IN THEIR FIRST YEAR OF LIVING
The author summarizes the results of research of the antibacterial, antiviral and antifungal properties of multifunctional human protein — lactoferrin, in order to determine the prospects for its use in the prevention and treatment of infectious diseases of children in their fi...
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| Format: | Article |
| Language: | Russian |
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Union of pediatricians of Russia
2017-02-01
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| Series: | Педиатрическая фармакология |
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| Online Access: | https://www.pedpharma.ru/jour/article/view/1488 |
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| author | P. E. Sadchikov I. G. Goldman L. S. Namazova-Baranova G. V. Yatsik T. E. Borovik A. D. Chernousov А. I. Romanchenko E. R. Sadchikova O. L. Lukoyanova N. G. Zvonkova I. A. Belyaeva |
| author_facet | P. E. Sadchikov I. G. Goldman L. S. Namazova-Baranova G. V. Yatsik T. E. Borovik A. D. Chernousov А. I. Romanchenko E. R. Sadchikova O. L. Lukoyanova N. G. Zvonkova I. A. Belyaeva |
| author_sort | P. E. Sadchikov |
| collection | DOAJ |
| description | The author summarizes the results of research of the antibacterial, antiviral and antifungal properties of multifunctional human protein — lactoferrin, in order to determine the prospects for its use in the prevention and treatment of infectious diseases of children in their first year of life. The mechanisms of anti-infectious effect of this protein with breastfed children have been described. Basic differences between human lactoferrin and cattle lactoferrin have been shown. Biotechnology of obtaining recombinant human lactoferrin from the milk of genetically engineered dairy animals (goat-producers) has been described. According to the studies, both by physical and chemical parameters and biological activity, human lactoferrin, obtained from milk-producing goats, corresponds to its natural counterpart. |
| format | Article |
| id | doaj-art-d9789a99fe804cbb872311edfb81dd4f |
| institution | DOAJ |
| issn | 1727-5776 2500-3089 |
| language | Russian |
| publishDate | 2017-02-01 |
| publisher | Union of pediatricians of Russia |
| record_format | Article |
| series | Педиатрическая фармакология |
| spelling | doaj-art-d9789a99fe804cbb872311edfb81dd4f2025-08-20T03:19:41ZrusUnion of pediatricians of RussiaПедиатрическая фармакология1727-57762500-30892017-02-0113660761310.15690/pf.v13i6.16771465LACTOFERIN IN THE PROBLEM OF ANTI-INFECTIOUS PROTECTION OF BABIES IN THEIR FIRST YEAR OF LIVINGP. E. Sadchikov0I. G. Goldman1L. S. Namazova-Baranova2G. V. Yatsik3T. E. Borovik4A. D. Chernousov5А. I. Romanchenko6E. R. Sadchikova7O. L. Lukoyanova8N. G. Zvonkova9I. A. Belyaeva10Scientific Center of Children’s HealthInstitute of Gene BiologyScientific Center of Children’s Health; Sechenov First Moscow State Medical University; N.I. Pirogov Russian National Research Medical UniversityScientific Center of Children’s HealthScientific Center of Children’s Health; Sechenov First Moscow State Medical UniversityInstitute of Gene Biology; Institute of Immunology, State Science CenterInstitute of Gene BiologyInstitute of Gene BiologyScientific Center of Children’s HealthScientific Center of Children’s Health; Sechenov First Moscow State Medical UniversityScientific Center of Children’s HealthThe author summarizes the results of research of the antibacterial, antiviral and antifungal properties of multifunctional human protein — lactoferrin, in order to determine the prospects for its use in the prevention and treatment of infectious diseases of children in their first year of life. The mechanisms of anti-infectious effect of this protein with breastfed children have been described. Basic differences between human lactoferrin and cattle lactoferrin have been shown. Biotechnology of obtaining recombinant human lactoferrin from the milk of genetically engineered dairy animals (goat-producers) has been described. According to the studies, both by physical and chemical parameters and biological activity, human lactoferrin, obtained from milk-producing goats, corresponds to its natural counterpart.https://www.pedpharma.ru/jour/article/view/1488childrenlactoferrinantibiotics-resistant microflorainfection pathology |
| spellingShingle | P. E. Sadchikov I. G. Goldman L. S. Namazova-Baranova G. V. Yatsik T. E. Borovik A. D. Chernousov А. I. Romanchenko E. R. Sadchikova O. L. Lukoyanova N. G. Zvonkova I. A. Belyaeva LACTOFERIN IN THE PROBLEM OF ANTI-INFECTIOUS PROTECTION OF BABIES IN THEIR FIRST YEAR OF LIVING Педиатрическая фармакология children lactoferrin antibiotics-resistant microflora infection pathology |
| title | LACTOFERIN IN THE PROBLEM OF ANTI-INFECTIOUS PROTECTION OF BABIES IN THEIR FIRST YEAR OF LIVING |
| title_full | LACTOFERIN IN THE PROBLEM OF ANTI-INFECTIOUS PROTECTION OF BABIES IN THEIR FIRST YEAR OF LIVING |
| title_fullStr | LACTOFERIN IN THE PROBLEM OF ANTI-INFECTIOUS PROTECTION OF BABIES IN THEIR FIRST YEAR OF LIVING |
| title_full_unstemmed | LACTOFERIN IN THE PROBLEM OF ANTI-INFECTIOUS PROTECTION OF BABIES IN THEIR FIRST YEAR OF LIVING |
| title_short | LACTOFERIN IN THE PROBLEM OF ANTI-INFECTIOUS PROTECTION OF BABIES IN THEIR FIRST YEAR OF LIVING |
| title_sort | lactoferin in the problem of anti infectious protection of babies in their first year of living |
| topic | children lactoferrin antibiotics-resistant microflora infection pathology |
| url | https://www.pedpharma.ru/jour/article/view/1488 |
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