LKB1 regulates ILC3 postnatal development and effector function through metabolic programming

LKB1 regulates ILC3 postnatal development and effector function through metabolic programming

IntroductionGroup 3 Innate Lymphoid Cells (ILC3s) are important for maintaining intestinal homeostasis and host defense. Emerging studies have shown that metabolic regulation plays a crucial role in regulating ILC3 activation and function. However, the role of Liver Kinase B1 (LKB1), a key metabolic...

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Bibliographic Details
Main Authors: Huasheng Zhang, Linfeng Zhao, Qingbing Zhang, Lin Hu, Xiaohui Su, Jiping Sun, Lei Shen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
group 3 innate lymphoid cells (ILC3s)
Liver Kinase B1 (LKB1)
metabolic programming
intestinal immune homeostasis
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1587256/full
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