From Conventional to Smart Prosthetics: Redefining Complete Denture Therapy Through Technology and Regenerative Science

<i>Background and Objectives:</i> Complete dentures remain a primary solution for oral rehabilitation in aging and medically compromised populations. The integration of digital workflows, regenerative materials, and smart technologies is propelling prosthodontics towards a new era, trans...

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Main Authors: Andrea Bors, Simona Mucenic, Adriana Monea, Alina Ormenisan, Gabriela Beresescu
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Medicina
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Online Access:https://www.mdpi.com/1648-9144/61/6/1104
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author Andrea Bors
Simona Mucenic
Adriana Monea
Alina Ormenisan
Gabriela Beresescu
author_facet Andrea Bors
Simona Mucenic
Adriana Monea
Alina Ormenisan
Gabriela Beresescu
author_sort Andrea Bors
collection DOAJ
description <i>Background and Objectives:</i> Complete dentures remain a primary solution for oral rehabilitation in aging and medically compromised populations. The integration of digital workflows, regenerative materials, and smart technologies is propelling prosthodontics towards a new era, transcending the limitations of traditional static prostheses. <i>Materials and Methods:</i> This narrative review synthesizes historical developments, current practices, and future innovations in complete denture therapy. A comprehensive review of literature from PubMed, Scopus, and Web of Science (2000–2025) was conducted, with a focus on materials science, digital design, patient-centered care, artificial intelligence (AI), and sustainable fabrication. <i>Results:</i> Innovations in the field include high-performance polymers, CAD–CAM systems, digital impressions, smart sensors, and bioactive liners. Recent trends in the field include the development of self-monitoring prostheses, artificial intelligence (AI)-driven design platforms, and bioprinted regenerative bases. These advances have been shown to enhance customization, durability, hygiene, and patient satisfaction. However, challenges persist in terms of accessibility, clinician training, regulatory validation, and ethical integration of digital data. <i>Conclusions:</i> The field of complete denture therapy is undergoing a transition toward a new paradigm of prosthetics that are personalized, intelligent, and sustainable. To ensure the integration of these technologies into standard care, ongoing interdisciplinary research, clinical validation, and equitable implementation are imperative.
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spelling doaj-art-d966b86e4e5944aa91c2f7a150384b032025-08-20T03:27:21ZengMDPI AGMedicina1010-660X1648-91442025-06-01616110410.3390/medicina61061104From Conventional to Smart Prosthetics: Redefining Complete Denture Therapy Through Technology and Regenerative ScienceAndrea Bors0Simona Mucenic1Adriana Monea2Alina Ormenisan3Gabriela Beresescu4Faculty of Dental Medicine, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, 38 Gh. Marinescu Str., 540139 Târgu Mureș, RomaniaFaculty of Dental Medicine, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, 38 Gh. Marinescu Str., 540139 Târgu Mureș, RomaniaFaculty of Dental Medicine, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, 38 Gh. Marinescu Str., 540139 Târgu Mureș, RomaniaFaculty of Dental Medicine, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, 38 Gh. Marinescu Str., 540139 Târgu Mureș, RomaniaFaculty of Dental Medicine, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, 38 Gh. Marinescu Str., 540139 Târgu Mureș, Romania<i>Background and Objectives:</i> Complete dentures remain a primary solution for oral rehabilitation in aging and medically compromised populations. The integration of digital workflows, regenerative materials, and smart technologies is propelling prosthodontics towards a new era, transcending the limitations of traditional static prostheses. <i>Materials and Methods:</i> This narrative review synthesizes historical developments, current practices, and future innovations in complete denture therapy. A comprehensive review of literature from PubMed, Scopus, and Web of Science (2000–2025) was conducted, with a focus on materials science, digital design, patient-centered care, artificial intelligence (AI), and sustainable fabrication. <i>Results:</i> Innovations in the field include high-performance polymers, CAD–CAM systems, digital impressions, smart sensors, and bioactive liners. Recent trends in the field include the development of self-monitoring prostheses, artificial intelligence (AI)-driven design platforms, and bioprinted regenerative bases. These advances have been shown to enhance customization, durability, hygiene, and patient satisfaction. However, challenges persist in terms of accessibility, clinician training, regulatory validation, and ethical integration of digital data. <i>Conclusions:</i> The field of complete denture therapy is undergoing a transition toward a new paradigm of prosthetics that are personalized, intelligent, and sustainable. To ensure the integration of these technologies into standard care, ongoing interdisciplinary research, clinical validation, and equitable implementation are imperative.https://www.mdpi.com/1648-9144/61/6/1104complete denturedigital dentistryregenerative dentistrysmart prostheticsCAD–CAMedentulism rehabilitation
spellingShingle Andrea Bors
Simona Mucenic
Adriana Monea
Alina Ormenisan
Gabriela Beresescu
From Conventional to Smart Prosthetics: Redefining Complete Denture Therapy Through Technology and Regenerative Science
Medicina
complete denture
digital dentistry
regenerative dentistry
smart prosthetics
CAD–CAM
edentulism rehabilitation
title From Conventional to Smart Prosthetics: Redefining Complete Denture Therapy Through Technology and Regenerative Science
title_full From Conventional to Smart Prosthetics: Redefining Complete Denture Therapy Through Technology and Regenerative Science
title_fullStr From Conventional to Smart Prosthetics: Redefining Complete Denture Therapy Through Technology and Regenerative Science
title_full_unstemmed From Conventional to Smart Prosthetics: Redefining Complete Denture Therapy Through Technology and Regenerative Science
title_short From Conventional to Smart Prosthetics: Redefining Complete Denture Therapy Through Technology and Regenerative Science
title_sort from conventional to smart prosthetics redefining complete denture therapy through technology and regenerative science
topic complete denture
digital dentistry
regenerative dentistry
smart prosthetics
CAD–CAM
edentulism rehabilitation
url https://www.mdpi.com/1648-9144/61/6/1104
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