Can Ethiopia eliminate malaria? Malaria burden: insights from the pre-elimination era, current challenges and perspectives
BackgroundEthiopia has faced a significant burden of malaria, enduring endemic transmission in various regions. Despite concerted efforts spanning years, malaria remains a persistent public health issue, particularly affecting underserved rural communities. Previous developments in vector control, d...
Saved in:
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-01-01
|
| Series: | Frontiers in Malaria |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmala.2025.1492444/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832582059519901696 |
|---|---|
| author | Dagmawi Woldesenbet Yalewayker Tegegne Abdulhakim Mussema Elias Tamene Kemal Mohamed Wagaw Abebe Melese Mekuria Kasahun Bogale Habtamu Geremew Mufta Muzemil Shifa Mulugeta Aemero Tegegne |
| author_facet | Dagmawi Woldesenbet Yalewayker Tegegne Abdulhakim Mussema Elias Tamene Kemal Mohamed Wagaw Abebe Melese Mekuria Kasahun Bogale Habtamu Geremew Mufta Muzemil Shifa Mulugeta Aemero Tegegne |
| author_sort | Dagmawi Woldesenbet |
| collection | DOAJ |
| description | BackgroundEthiopia has faced a significant burden of malaria, enduring endemic transmission in various regions. Despite concerted efforts spanning years, malaria remains a persistent public health issue, particularly affecting underserved rural communities. Previous developments in vector control, diagnostic capabilities, and treatment protocols have led to notable reductions in malaria morbidity and mortality. However, challenges persist, including the emergence of drug and insecticide resistance, compounded by environmental and demographic factors. Understanding the historical context and contemporary challenges is crucial for navigating Ethiopia’s path toward malaria elimination.MethodsFrom October 2023 to January 2024, a systematic search was conducted across open access journals such as PubMed, EMBASE, CINALH, Web of Science, Global Health, and Google Scholar using MeSH and Emtree terms for malaria. The focus was on challenges of malaria elimination in Ethiopia, such as drug resistance, vectors’ insecticide resistance and the loss of the diagnostic potential of rapid diagnostic kits.Main textRecent trend analyses and World Health Organization reports indicate resurgence in malaria cases in Ethiopia. Factors contributing to this resurgence include emerging drug resistance, insecticide resistance, and genetic mutations such as single nucleotide polymorphisms. Other challenges include the spreading resistance to effective antimalarial drugs, socio-cultural barriers to malaria elimination, the challenge posed by Plasmodium vivax in elimination efforts, and the occurrence of imported cases in previously low burden areas. To reverse the rising trend of malaria cases, it is necessary to customize intervention strategies through active community engagement, rigorous healthcare infrastructure, and learning from countries that have successfully eliminated malaria.ConclusionWhile past successes are notable, they do not guarantee current progress, highlighting the need for rigorous implementation of strategies and adaptation of intervention methods to ensure the success of malaria elimination efforts. However, recent data suggests a concerning resurgence in malaria cases, potentially fueled by emerging drug and insecticide resistance. To achieve sustained success in malaria elimination, there is an urgent need for continued vigilance, customization of intervention strategies, and robust collaboration between stakeholders to address these challenges effectively. |
| format | Article |
| id | doaj-art-d9621ec19109467bacadf5b9174b5369 |
| institution | Kabale University |
| issn | 2813-7396 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Malaria |
| spelling | doaj-art-d9621ec19109467bacadf5b9174b53692025-01-30T06:21:58ZengFrontiers Media S.A.Frontiers in Malaria2813-73962025-01-01310.3389/fmala.2025.14924441492444Can Ethiopia eliminate malaria? Malaria burden: insights from the pre-elimination era, current challenges and perspectivesDagmawi Woldesenbet0Yalewayker Tegegne1Abdulhakim Mussema2Elias Tamene3Kemal Mohamed4Wagaw Abebe5Melese Mekuria6Kasahun Bogale7Habtamu Geremew8Mufta Muzemil Shifa9Mulugeta Aemero Tegegne10Department of Medical Laboratory Science, College of Medicine and Health Science, Wachemo University, Hossana, EthiopiaDepartment of Medical Parasitology, School of Biomedical and Laboratory Science, College of Medicine and Health Science, University of Gondar, Gondar, EthiopiaDepartment of Medical Laboratory Science, College of Medicine and Health Science, Wachemo University, Hossana, EthiopiaDepartment of Medical Laboratory Science, College of Medicine and Health Science, Wachemo University, Hossana, EthiopiaDepartment of Medical Laboratory Science, College of Medicine and Health Science, Wachemo University, Hossana, EthiopiaDepartment of Medical Laboratory Science, College of Health Science, Woldia University, Woldia, EthiopiaDepartment of Medical Laboratory Science, Hossana College of Health Science, Hossana, EthiopiaDepartment of Medical Laboratory Science, College of Medicine and Health Science, Wachemo University, Hossana, EthiopiaCollege of Health Science, Oda Bultum University, Chiro, EthiopiaDepartment of Medical Laboratory Science, College of Medicine and Health Science, Worabe University, Worabe, EthiopiaDepartment of Medical Parasitology, School of Biomedical and Laboratory Science, College of Medicine and Health Science, University of Gondar, Gondar, EthiopiaBackgroundEthiopia has faced a significant burden of malaria, enduring endemic transmission in various regions. Despite concerted efforts spanning years, malaria remains a persistent public health issue, particularly affecting underserved rural communities. Previous developments in vector control, diagnostic capabilities, and treatment protocols have led to notable reductions in malaria morbidity and mortality. However, challenges persist, including the emergence of drug and insecticide resistance, compounded by environmental and demographic factors. Understanding the historical context and contemporary challenges is crucial for navigating Ethiopia’s path toward malaria elimination.MethodsFrom October 2023 to January 2024, a systematic search was conducted across open access journals such as PubMed, EMBASE, CINALH, Web of Science, Global Health, and Google Scholar using MeSH and Emtree terms for malaria. The focus was on challenges of malaria elimination in Ethiopia, such as drug resistance, vectors’ insecticide resistance and the loss of the diagnostic potential of rapid diagnostic kits.Main textRecent trend analyses and World Health Organization reports indicate resurgence in malaria cases in Ethiopia. Factors contributing to this resurgence include emerging drug resistance, insecticide resistance, and genetic mutations such as single nucleotide polymorphisms. Other challenges include the spreading resistance to effective antimalarial drugs, socio-cultural barriers to malaria elimination, the challenge posed by Plasmodium vivax in elimination efforts, and the occurrence of imported cases in previously low burden areas. To reverse the rising trend of malaria cases, it is necessary to customize intervention strategies through active community engagement, rigorous healthcare infrastructure, and learning from countries that have successfully eliminated malaria.ConclusionWhile past successes are notable, they do not guarantee current progress, highlighting the need for rigorous implementation of strategies and adaptation of intervention methods to ensure the success of malaria elimination efforts. However, recent data suggests a concerning resurgence in malaria cases, potentially fueled by emerging drug and insecticide resistance. To achieve sustained success in malaria elimination, there is an urgent need for continued vigilance, customization of intervention strategies, and robust collaboration between stakeholders to address these challenges effectively.https://www.frontiersin.org/articles/10.3389/fmala.2025.1492444/fullmalariaPlasmodiumEthiopiatrend analysiselimination |
| spellingShingle | Dagmawi Woldesenbet Yalewayker Tegegne Abdulhakim Mussema Elias Tamene Kemal Mohamed Wagaw Abebe Melese Mekuria Kasahun Bogale Habtamu Geremew Mufta Muzemil Shifa Mulugeta Aemero Tegegne Can Ethiopia eliminate malaria? Malaria burden: insights from the pre-elimination era, current challenges and perspectives Frontiers in Malaria malaria Plasmodium Ethiopia trend analysis elimination |
| title | Can Ethiopia eliminate malaria? Malaria burden: insights from the pre-elimination era, current challenges and perspectives |
| title_full | Can Ethiopia eliminate malaria? Malaria burden: insights from the pre-elimination era, current challenges and perspectives |
| title_fullStr | Can Ethiopia eliminate malaria? Malaria burden: insights from the pre-elimination era, current challenges and perspectives |
| title_full_unstemmed | Can Ethiopia eliminate malaria? Malaria burden: insights from the pre-elimination era, current challenges and perspectives |
| title_short | Can Ethiopia eliminate malaria? Malaria burden: insights from the pre-elimination era, current challenges and perspectives |
| title_sort | can ethiopia eliminate malaria malaria burden insights from the pre elimination era current challenges and perspectives |
| topic | malaria Plasmodium Ethiopia trend analysis elimination |
| url | https://www.frontiersin.org/articles/10.3389/fmala.2025.1492444/full |
| work_keys_str_mv | AT dagmawiwoldesenbet canethiopiaeliminatemalariamalariaburdeninsightsfromthepreeliminationeracurrentchallengesandperspectives AT yalewaykertegegne canethiopiaeliminatemalariamalariaburdeninsightsfromthepreeliminationeracurrentchallengesandperspectives AT abdulhakimmussema canethiopiaeliminatemalariamalariaburdeninsightsfromthepreeliminationeracurrentchallengesandperspectives AT eliastamene canethiopiaeliminatemalariamalariaburdeninsightsfromthepreeliminationeracurrentchallengesandperspectives AT kemalmohamed canethiopiaeliminatemalariamalariaburdeninsightsfromthepreeliminationeracurrentchallengesandperspectives AT wagawabebe canethiopiaeliminatemalariamalariaburdeninsightsfromthepreeliminationeracurrentchallengesandperspectives AT melesemekuria canethiopiaeliminatemalariamalariaburdeninsightsfromthepreeliminationeracurrentchallengesandperspectives AT kasahunbogale canethiopiaeliminatemalariamalariaburdeninsightsfromthepreeliminationeracurrentchallengesandperspectives AT habtamugeremew canethiopiaeliminatemalariamalariaburdeninsightsfromthepreeliminationeracurrentchallengesandperspectives AT muftamuzemilshifa canethiopiaeliminatemalariamalariaburdeninsightsfromthepreeliminationeracurrentchallengesandperspectives AT mulugetaaemerotegegne canethiopiaeliminatemalariamalariaburdeninsightsfromthepreeliminationeracurrentchallengesandperspectives |