Ginsenoside Rg5 alleviates hypoxia-induced myocardial apoptosis by targeting STAT3 to promote Tyr705 phosphorylation

Ginsenoside Rg5 alleviates hypoxia-induced myocardial apoptosis by targeting STAT3 to promote Tyr705 phosphorylation

Abstract Background The heart, as the body's blood-pumping organ, is extremely sensitive to changes in oxygen levels. Myocardial injury caused by hypoxia is a challenging issue, and there are currently no definitive specific drugs available for its treatment. Ginsenoside Rg5, one of the main ra...

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Main Authors: Fang-yang Li, Yi-hao Wang, Cheng Zhang, Wan-yun Dang, Ze-kun Wu, Zhen-hui Wu, Jia-lu Cui, Xiang-jun Wu, Chun-qi Yang, Xue-cong Tian, Cheng-rong Xiao, Yu-guang Wang, Yue Gao
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Chinese Medicine
Subjects:
Ginsenoside Rg5
Stat3
Tyr705 phosphorylation
Hypoxia
Myocardial apoptosis
Online Access:https://doi.org/10.1186/s13020-025-01128-8
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