Anesthesia Management of a Child with Mosaic Trisomy 22 for Adenotonsillectomy Surgery

Mosaic trisomy 22 is a very rare autosomal anomaly with variability of organ malformations and developmental defects. There are fewer than 23 reports in the literature of live born children describing their neurodevelopmental outcome. Sometimes in clinical practice, anesthesiologists confront a rar...

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Main Authors: Masoud Tarbiat, Mohammad Hossein Bakhshaei, Rohollah Abbasi, Mahmoud Rezaei
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2024-07-01
Series:Archives of Anesthesia and Critical Care
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Online Access:https://aacc.tums.ac.ir/index.php/aacc/article/view/954
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author Masoud Tarbiat
Mohammad Hossein Bakhshaei
Rohollah Abbasi
Mahmoud Rezaei
author_facet Masoud Tarbiat
Mohammad Hossein Bakhshaei
Rohollah Abbasi
Mahmoud Rezaei
author_sort Masoud Tarbiat
collection DOAJ
description Mosaic trisomy 22 is a very rare autosomal anomaly with variability of organ malformations and developmental defects. There are fewer than 23 reports in the literature of live born children describing their neurodevelopmental outcome. Sometimes in clinical practice, anesthesiologists confront a rare clinical case with no paper published on it or having previous experience about it. Therefore, they face a serious challenge in anesthesia managing and selecting drugs for them (like our case). So, we reported our experience about a child (aged 8) with mosaic trisomy 22 who had anesthesia for adenotonsillectomy surgery.  Previously, he had a history of seizure and variety of surgeries for congenital anomalies. He also had been treated for congenital hypothyroidism and gastroesophageal reflux disease. The anesthesia performed with midazolam, fentanyl, sodium thiopental, atracurium and isoflurane in O2:N2o (50:50). The operation was uneventful and he was completely awakened in recovery room. This report emphasizes that in some situation, this approach could be used safely for anesthesia management in these patients.
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series Archives of Anesthesia and Critical Care
spelling doaj-art-d95c8cced51e48f6bd8adc6a47833ea42025-08-20T02:20:58ZengTehran University of Medical SciencesArchives of Anesthesia and Critical Care2423-58492024-07-0110Supp. 2Anesthesia Management of a Child with Mosaic Trisomy 22 for Adenotonsillectomy SurgeryMasoud Tarbiat0Mohammad Hossein Bakhshaei1Rohollah Abbasi2Mahmoud Rezaei3Department of Anesthesiology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.Department of Anesthesiology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.Department of Otolaryngology Head and Neck Surgery, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.Department of Anesthesiology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran. Mosaic trisomy 22 is a very rare autosomal anomaly with variability of organ malformations and developmental defects. There are fewer than 23 reports in the literature of live born children describing their neurodevelopmental outcome. Sometimes in clinical practice, anesthesiologists confront a rare clinical case with no paper published on it or having previous experience about it. Therefore, they face a serious challenge in anesthesia managing and selecting drugs for them (like our case). So, we reported our experience about a child (aged 8) with mosaic trisomy 22 who had anesthesia for adenotonsillectomy surgery.  Previously, he had a history of seizure and variety of surgeries for congenital anomalies. He also had been treated for congenital hypothyroidism and gastroesophageal reflux disease. The anesthesia performed with midazolam, fentanyl, sodium thiopental, atracurium and isoflurane in O2:N2o (50:50). The operation was uneventful and he was completely awakened in recovery room. This report emphasizes that in some situation, this approach could be used safely for anesthesia management in these patients. https://aacc.tums.ac.ir/index.php/aacc/article/view/954Trisomy 22 mosaicism syndromeAnesthesiaAtrial Septal DefecthypothyroidismCleft Palate
spellingShingle Masoud Tarbiat
Mohammad Hossein Bakhshaei
Rohollah Abbasi
Mahmoud Rezaei
Anesthesia Management of a Child with Mosaic Trisomy 22 for Adenotonsillectomy Surgery
Archives of Anesthesia and Critical Care
Trisomy 22 mosaicism syndrome
Anesthesia
Atrial Septal Defect
hypothyroidism
Cleft Palate
title Anesthesia Management of a Child with Mosaic Trisomy 22 for Adenotonsillectomy Surgery
title_full Anesthesia Management of a Child with Mosaic Trisomy 22 for Adenotonsillectomy Surgery
title_fullStr Anesthesia Management of a Child with Mosaic Trisomy 22 for Adenotonsillectomy Surgery
title_full_unstemmed Anesthesia Management of a Child with Mosaic Trisomy 22 for Adenotonsillectomy Surgery
title_short Anesthesia Management of a Child with Mosaic Trisomy 22 for Adenotonsillectomy Surgery
title_sort anesthesia management of a child with mosaic trisomy 22 for adenotonsillectomy surgery
topic Trisomy 22 mosaicism syndrome
Anesthesia
Atrial Septal Defect
hypothyroidism
Cleft Palate
url https://aacc.tums.ac.ir/index.php/aacc/article/view/954
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AT mohammadhosseinbakhshaei anesthesiamanagementofachildwithmosaictrisomy22foradenotonsillectomysurgery
AT rohollahabbasi anesthesiamanagementofachildwithmosaictrisomy22foradenotonsillectomysurgery
AT mahmoudrezaei anesthesiamanagementofachildwithmosaictrisomy22foradenotonsillectomysurgery