Influence of genetic polymorphism of oncogenic viruses on the risk of human tumors and their specific prevention
Numerous studies have shown that approximately 20 % of all human tumors are neoplasms of an infectious nature. This review is an attempt to summarize the current understanding of the role of known human oncogenic viruses and their genetic variants on the risk of the human cancers development, as wel...
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| Format: | Article |
| Language: | Russian |
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ABV-press
2015-06-01
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| Series: | Успехи молекулярной онкологии |
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| Online Access: | https://umo.abvpress.ru/jour/article/view/15 |
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| author | V. E. Gurtsevich N. B. Senyuta K. V. Smirnova |
| author_facet | V. E. Gurtsevich N. B. Senyuta K. V. Smirnova |
| author_sort | V. E. Gurtsevich |
| collection | DOAJ |
| description | Numerous studies have shown that approximately 20 % of all human tumors are neoplasms of an infectious nature. This review is an attempt to summarize the current understanding of the role of known human oncogenic viruses and their genetic variants on the risk of the human cancers development, as well as to show the existing measures of specific prevention of virus-induced tumors. It was paid also attention to the interaction between viral and cellular proteins, including tumor suppressors, and to the evaluation the significance of this interaction for specific oncogenic viruses and virus-associated tumors. |
| format | Article |
| id | doaj-art-d958e7de2cdc45468e05817c7db47278 |
| institution | Kabale University |
| issn | 2313-805X 2413-3787 |
| language | Russian |
| publishDate | 2015-06-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Успехи молекулярной онкологии |
| spelling | doaj-art-d958e7de2cdc45468e05817c7db472782025-08-20T03:44:06ZrusABV-pressУспехи молекулярной онкологии2313-805X2413-37872015-06-0111364710.17650/2313-805X.2014.1.1.36-4715Influence of genetic polymorphism of oncogenic viruses on the risk of human tumors and their specific preventionV. E. Gurtsevich0N. B. Senyuta1K. V. Smirnova2Federal State Budgetary Institution “N. N. Blokhin Russian Cancer Research Center“, Russian Academy of Medical Sciences, MoscowFederal State Budgetary Institution “N. N. Blokhin Russian Cancer Research Center“, Russian Academy of Medical Sciences, MoscowFederal State Budgetary Institution “N. N. Blokhin Russian Cancer Research Center“, Russian Academy of Medical Sciences, MoscowNumerous studies have shown that approximately 20 % of all human tumors are neoplasms of an infectious nature. This review is an attempt to summarize the current understanding of the role of known human oncogenic viruses and their genetic variants on the risk of the human cancers development, as well as to show the existing measures of specific prevention of virus-induced tumors. It was paid also attention to the interaction between viral and cellular proteins, including tumor suppressors, and to the evaluation the significance of this interaction for specific oncogenic viruses and virus-associated tumors.https://umo.abvpress.ru/jour/article/view/15human papilloma virushepatitis b virushepatitis c viruskaposi's sarcoma virushuman t cell leukemia virushuman endogenous retrovirusesmerkel cell polyomavirusepstein–barr viruslmp1 polymorphismsignaling pathways onkolytic viruses |
| spellingShingle | V. E. Gurtsevich N. B. Senyuta K. V. Smirnova Influence of genetic polymorphism of oncogenic viruses on the risk of human tumors and their specific prevention Успехи молекулярной онкологии human papilloma virus hepatitis b virus hepatitis c virus kaposi's sarcoma virus human t cell leukemia virus human endogenous retroviruses merkel cell polyomavirus epstein–barr virus lmp1 polymorphism signaling pathways onkolytic viruses |
| title | Influence of genetic polymorphism of oncogenic viruses on the risk of human tumors and their specific prevention |
| title_full | Influence of genetic polymorphism of oncogenic viruses on the risk of human tumors and their specific prevention |
| title_fullStr | Influence of genetic polymorphism of oncogenic viruses on the risk of human tumors and their specific prevention |
| title_full_unstemmed | Influence of genetic polymorphism of oncogenic viruses on the risk of human tumors and their specific prevention |
| title_short | Influence of genetic polymorphism of oncogenic viruses on the risk of human tumors and their specific prevention |
| title_sort | influence of genetic polymorphism of oncogenic viruses on the risk of human tumors and their specific prevention |
| topic | human papilloma virus hepatitis b virus hepatitis c virus kaposi's sarcoma virus human t cell leukemia virus human endogenous retroviruses merkel cell polyomavirus epstein–barr virus lmp1 polymorphism signaling pathways onkolytic viruses |
| url | https://umo.abvpress.ru/jour/article/view/15 |
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