Topical insulin improves postoperative wound healing in controlled diabetic patients through regulating the expression of E-Cadherin and Ki67: an open-label randomized controlled-trial

Topical insulin improves postoperative wound healing in controlled diabetic patients through regulating the expression of E-Cadherin and Ki67: an open-label randomized controlled-trial

Abstract Background Diabetic patients are at a significantly higher risk of delayed and impaired wound healing, with increased susceptibility to wound infections and dehiscence. The pathophysiology of abnormal wound healing in diabetes is multifactorial, involving impaired vascularization, reduced c...

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Bibliographic Details
Main Authors: Mahmoud Ahmed Khattab, Omnia Azmy Nabeh, Sara Adel, Mahmoud Abdelazeem, Mohamed M. Naser, Lamiaa Mohammed Matter
Format: Article
Language:English
Published: SpringerOpen 2025-06-01
Series:Future Journal of Pharmaceutical Sciences
Subjects:
Diabetes
E-cadherin
Healing
Insulin, Ki67
Postoperative wound
Online Access:https://doi.org/10.1186/s43094-025-00830-6
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