Esophageal Plasmacytoma Revealed by Persistent Hiccups: A Case Report and Literature Review
Introduction. Solitary extramedullary plasmacytoma (SEP) is a rare neoplasm that is derived from monoclonal proliferation of plasma cells in the soft tissues or organs arising outside the bone marrow. It is present in about 3% of all plasma cell tumors and originates mainly from the upper respirator...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Case Reports in Gastrointestinal Medicine |
| Online Access: | http://dx.doi.org/10.1155/2022/2242768 |
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| author | Khaoula Khalil Fatima Ezzahra Lahlimi Illias Tazi |
| author_facet | Khaoula Khalil Fatima Ezzahra Lahlimi Illias Tazi |
| author_sort | Khaoula Khalil |
| collection | DOAJ |
| description | Introduction. Solitary extramedullary plasmacytoma (SEP) is a rare neoplasm that is derived from monoclonal proliferation of plasma cells in the soft tissues or organs arising outside the bone marrow. It is present in about 3% of all plasma cell tumors and originates mainly from the upper respiratory tract and nasopharynx. Involvement of the esophagus is exceptionally seen in cases of SEP. Case Presentation. We report a novel case of a 74-year-old male patient attended with a 6-month history of hiccupping further associated with dysphasia and weight loss all caused by esophageal plasmacytoma. Histological and immunohistochemical examination of the tumor confirmed the diagnosis of plasmacytoma. Workup for the multiple myeloma came out to be negative, thus confirming the diagnosis of SEP. The patient was treated with radiotherapy alone, leading to complete remission (at 30 months of follow-up). Conclusion. Esophageal plasmacytoma, an exceptional presentation of extramedullary plasmacytoma, should be kept in mind while dealing with patients presenting with intractable hiccups. |
| format | Article |
| id | doaj-art-d94fb5ae92cd48b89eda54223f1a3732 |
| institution | OA Journals |
| issn | 2090-6536 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Gastrointestinal Medicine |
| spelling | doaj-art-d94fb5ae92cd48b89eda54223f1a37322025-08-20T02:21:25ZengWileyCase Reports in Gastrointestinal Medicine2090-65362022-01-01202210.1155/2022/2242768Esophageal Plasmacytoma Revealed by Persistent Hiccups: A Case Report and Literature ReviewKhaoula Khalil0Fatima Ezzahra Lahlimi1Illias Tazi2Department of Hematology and Bone Marrow TransplantationDepartment of Hematology and Bone Marrow TransplantationDepartment of Hematology and Bone Marrow TransplantationIntroduction. Solitary extramedullary plasmacytoma (SEP) is a rare neoplasm that is derived from monoclonal proliferation of plasma cells in the soft tissues or organs arising outside the bone marrow. It is present in about 3% of all plasma cell tumors and originates mainly from the upper respiratory tract and nasopharynx. Involvement of the esophagus is exceptionally seen in cases of SEP. Case Presentation. We report a novel case of a 74-year-old male patient attended with a 6-month history of hiccupping further associated with dysphasia and weight loss all caused by esophageal plasmacytoma. Histological and immunohistochemical examination of the tumor confirmed the diagnosis of plasmacytoma. Workup for the multiple myeloma came out to be negative, thus confirming the diagnosis of SEP. The patient was treated with radiotherapy alone, leading to complete remission (at 30 months of follow-up). Conclusion. Esophageal plasmacytoma, an exceptional presentation of extramedullary plasmacytoma, should be kept in mind while dealing with patients presenting with intractable hiccups.http://dx.doi.org/10.1155/2022/2242768 |
| spellingShingle | Khaoula Khalil Fatima Ezzahra Lahlimi Illias Tazi Esophageal Plasmacytoma Revealed by Persistent Hiccups: A Case Report and Literature Review Case Reports in Gastrointestinal Medicine |
| title | Esophageal Plasmacytoma Revealed by Persistent Hiccups: A Case Report and Literature Review |
| title_full | Esophageal Plasmacytoma Revealed by Persistent Hiccups: A Case Report and Literature Review |
| title_fullStr | Esophageal Plasmacytoma Revealed by Persistent Hiccups: A Case Report and Literature Review |
| title_full_unstemmed | Esophageal Plasmacytoma Revealed by Persistent Hiccups: A Case Report and Literature Review |
| title_short | Esophageal Plasmacytoma Revealed by Persistent Hiccups: A Case Report and Literature Review |
| title_sort | esophageal plasmacytoma revealed by persistent hiccups a case report and literature review |
| url | http://dx.doi.org/10.1155/2022/2242768 |
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