Using host and bacterial genetic approaches to define virulence strategies and protective immunity during Mycobacterium tuberculosis infection

Using host and bacterial genetic approaches to define virulence strategies and protective immunity during Mycobacterium tuberculosis infection

ABSTRACT Infections with Mycobacterium tuberculosis (Mtb) resulted in over one million deaths in 2024, the highest number for any infectious disease. With no vaccines that protect against pulmonary tuberculosis (TB) and the challenges associated with antibiotic therapy, there is a critical need to b...

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Bibliographic Details
Main Author: Andrew J. Olive
Format: Article
Language:English
Published: American Society for Microbiology 2025-05-01
Series:mSphere
Subjects:
Mycobacterium
genetics
host-pathogen interactions
immune evasion
Online Access:https://journals.asm.org/doi/10.1128/msphere.00517-24
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