Results of the preclinical multicenter randomized controlled paclitaxel-induced neuropathy prevention replication study (PINPRICS)

Results of the preclinical multicenter randomized controlled paclitaxel-induced neuropathy prevention replication study (PINPRICS)

Abstract Objective Chemotherapy-induced peripheral neuropathy (CIPN) is a frequent and serious side effect of many cytotoxic drugs, including paclitaxel. Despite the identification of treatment options in animal models, clinical trials for the treatment or prevention of CIPN have been negative. Majo...

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Main Authors: Wolfgang Boehmerle, Tim Hagenacker, Markus Leo, Linda-Isabell Schmitt, Helmar C. Lehmann, Ines Klein, Regina Stegherr, Frank Konietschke, Matthias Endres, Petra Huehnchen
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Research Notes
Subjects:
Chemotherapy-induced polyneuropathy
Neuropathic pain
Neuroprotection
Preclinical replication study
Online Access:https://doi.org/10.1186/s13104-025-07206-2
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