Cryptococcal meningitis post-covid-19 infection: Immunomodulation, a double-edged sword
Cryptococcal meningitis is an opportunistic infection associated with altered immunity. Immunomodulatory agent use in severe coronavirus disease 2019 (COVID-19) may predispose such infections. Here, we present a 75-year-old male patient who presented with fever and altered general status after seve...
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| Format: | Article |
| Language: | English |
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The Journal of Infection in Developing Countries
2023-05-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/17170 |
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| author | Hilal W Abdessamad Michel Achkar Amal Al Zoghbi Mohamad Fleifel Abdul Rahman Ousta Ahmad Kassar Nadia L Samaha Rita Nemr Anna Farra Jacques E Mokhbat Rola Husni |
| author_facet | Hilal W Abdessamad Michel Achkar Amal Al Zoghbi Mohamad Fleifel Abdul Rahman Ousta Ahmad Kassar Nadia L Samaha Rita Nemr Anna Farra Jacques E Mokhbat Rola Husni |
| author_sort | Hilal W Abdessamad |
| collection | DOAJ |
| description |
Cryptococcal meningitis is an opportunistic infection associated with altered immunity. Immunomodulatory agent use in severe coronavirus disease 2019 (COVID-19) may predispose such infections. Here, we present a 75-year-old male patient who presented with fever and altered general status after severe COVID-19 infection and developed cryptococcal meningitis. Opportunistic infection may arise from the use of immunomodulation in severe COVID-19, especially in the elderly population. This article describes the case and extensively reviews cryptococcal disease post-COVID-19 literature, highlighting the risk from immunosuppressive treatment.
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| format | Article |
| id | doaj-art-d933db58a2b747bf997cad50084ece18 |
| institution | OA Journals |
| issn | 1972-2680 |
| language | English |
| publishDate | 2023-05-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-d933db58a2b747bf997cad50084ece182025-08-20T02:14:07ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802023-05-01170510.3855/jidc.17170Cryptococcal meningitis post-covid-19 infection: Immunomodulation, a double-edged swordHilal W Abdessamad0Michel Achkar1Amal Al Zoghbi2Mohamad Fleifel3Abdul Rahman Ousta4Ahmad Kassar5Nadia L Samaha6Rita Nemr7Anna Farra8Jacques E Mokhbat9Rola Husni10Infectious Diseases, Lebanese American University School of Medicine and Lebanese American University Medical Center–Rizk Hospital, Beirut, LebanonInternal Medicine, Lebanese American University School of Medicine and Lebanese American University Medical Center–Rizk Hospital, Beirut, LebanonEndocrinology, Lebanese American University School of Medicine and Lebanese American University Medical Center–Rizk Hospital, Beirut, LebanonInternal Medicine, Lebanese American University School of Medicine and Lebanese American University Medical Center–Rizk Hospital, Beirut, LebanonLebanese American University School of Medicine and Lebanese American University Medical Center–Rizk Hospital, Beirut, LebanonLebanese American University School of Medicine and Lebanese American University Medical Center–Rizk Hospital, Beirut, LebanonGeorgetown University School of Medicine, Washington DC, United StatesEndocrinology, Lebanese American University School of Medicine and Lebanese American University Medical Center–Rizk Hospital, Beirut, LebanonInfectious Diseases, Lebanese American University School of Medicine and Lebanese American University Medical Center–Rizk Hospital, Beirut, LebanonInfectious Diseases, Lebanese American University School of Medicine and Lebanese American University Medical Center–Rizk Hospital, Beirut, LebanonInfectious Diseases, Lebanese American University School of Medicine and Lebanese American University Medical Center–Rizk Hospital, Beirut, Lebanon Cryptococcal meningitis is an opportunistic infection associated with altered immunity. Immunomodulatory agent use in severe coronavirus disease 2019 (COVID-19) may predispose such infections. Here, we present a 75-year-old male patient who presented with fever and altered general status after severe COVID-19 infection and developed cryptococcal meningitis. Opportunistic infection may arise from the use of immunomodulation in severe COVID-19, especially in the elderly population. This article describes the case and extensively reviews cryptococcal disease post-COVID-19 literature, highlighting the risk from immunosuppressive treatment. https://jidc.org/index.php/journal/article/view/17170cryptococcusmeningitisimmunomodulationCOVID-19 |
| spellingShingle | Hilal W Abdessamad Michel Achkar Amal Al Zoghbi Mohamad Fleifel Abdul Rahman Ousta Ahmad Kassar Nadia L Samaha Rita Nemr Anna Farra Jacques E Mokhbat Rola Husni Cryptococcal meningitis post-covid-19 infection: Immunomodulation, a double-edged sword Journal of Infection in Developing Countries cryptococcus meningitis immunomodulation COVID-19 |
| title | Cryptococcal meningitis post-covid-19 infection: Immunomodulation, a double-edged sword |
| title_full | Cryptococcal meningitis post-covid-19 infection: Immunomodulation, a double-edged sword |
| title_fullStr | Cryptococcal meningitis post-covid-19 infection: Immunomodulation, a double-edged sword |
| title_full_unstemmed | Cryptococcal meningitis post-covid-19 infection: Immunomodulation, a double-edged sword |
| title_short | Cryptococcal meningitis post-covid-19 infection: Immunomodulation, a double-edged sword |
| title_sort | cryptococcal meningitis post covid 19 infection immunomodulation a double edged sword |
| topic | cryptococcus meningitis immunomodulation COVID-19 |
| url | https://jidc.org/index.php/journal/article/view/17170 |
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