The Impact of Oral Contraceptive Use on Selected Vitamins and Minerals in Women of Reproductive Age

Childbearing women on combined oral contraceptive agents (COCAs) have been linked with the development of various diseases and possible deficiencies in serum micronutrients. This study aimed at investigating the vitamins and trace mineral changes associated with the use of COCAs among child-bearing...

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Main Authors: Ayman S. Abutair, Asmaa M. Meghari, Ihab A. Naser
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Proceedings
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Online Access:https://www.mdpi.com/2504-3900/88/1/1
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author Ayman S. Abutair
Asmaa M. Meghari
Ihab A. Naser
author_facet Ayman S. Abutair
Asmaa M. Meghari
Ihab A. Naser
author_sort Ayman S. Abutair
collection DOAJ
description Childbearing women on combined oral contraceptive agents (COCAs) have been linked with the development of various diseases and possible deficiencies in serum micronutrients. This study aimed at investigating the vitamins and trace mineral changes associated with the use of COCAs among child-bearing healthy women in the Gaza Strip. A comparative cross-sectional study was designed. After informed consent was obtained, questionnaires, anthropometric measurements, and blood samples were collected from a total of 90 women of childbearing age (45 used different contraceptive methods, and 45 used COCAs). The mean hemoglobin, hematocrit, and red blood cells that obtained from the COCAs users group were significantly lower than those in the non-users group (<i>p</i> < 0.001, <i>p</i> = 0.073, and <i>p</i> = 0.047, respectively). There was a significant association between the use of COCAs and cholesterol level (<i>p</i> = 0.044). In addition, there was a statistically significant difference in the levels of homocysteine and vitamin B6 between the groups (<i>p</i> = 0.008 and <i>p</i> = 0.010, respectively). The present study indicated the possibility of micronutrient deficiencies in women on combined oral contraceptive agents.
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spelling doaj-art-d9293a2d803d4e859faff4fa761b6c612025-08-20T02:21:53ZengMDPI AGProceedings2504-39002023-07-01881110.3390/proceedings2023088001The Impact of Oral Contraceptive Use on Selected Vitamins and Minerals in Women of Reproductive AgeAyman S. Abutair0Asmaa M. Meghari1Ihab A. Naser2Department of Clinical Nutrition, Palestinian MoH, Gaza 00970, PalestineMaster Program of Clinical Nutrition, Al-Azhar University Gaza (AUG), Gaza P.O. Box 405, PalestineDepartment of Clinical Nutrition, Faculty of Applied Medical Sciences, Al-Azhar University Gaza (AUG), Gaza P.O. Box 405, PalestineChildbearing women on combined oral contraceptive agents (COCAs) have been linked with the development of various diseases and possible deficiencies in serum micronutrients. This study aimed at investigating the vitamins and trace mineral changes associated with the use of COCAs among child-bearing healthy women in the Gaza Strip. A comparative cross-sectional study was designed. After informed consent was obtained, questionnaires, anthropometric measurements, and blood samples were collected from a total of 90 women of childbearing age (45 used different contraceptive methods, and 45 used COCAs). The mean hemoglobin, hematocrit, and red blood cells that obtained from the COCAs users group were significantly lower than those in the non-users group (<i>p</i> < 0.001, <i>p</i> = 0.073, and <i>p</i> = 0.047, respectively). There was a significant association between the use of COCAs and cholesterol level (<i>p</i> = 0.044). In addition, there was a statistically significant difference in the levels of homocysteine and vitamin B6 between the groups (<i>p</i> = 0.008 and <i>p</i> = 0.010, respectively). The present study indicated the possibility of micronutrient deficiencies in women on combined oral contraceptive agents.https://www.mdpi.com/2504-3900/88/1/1contraceptivesmicronutrientschildbearing ageGaza
spellingShingle Ayman S. Abutair
Asmaa M. Meghari
Ihab A. Naser
The Impact of Oral Contraceptive Use on Selected Vitamins and Minerals in Women of Reproductive Age
Proceedings
contraceptives
micronutrients
childbearing age
Gaza
title The Impact of Oral Contraceptive Use on Selected Vitamins and Minerals in Women of Reproductive Age
title_full The Impact of Oral Contraceptive Use on Selected Vitamins and Minerals in Women of Reproductive Age
title_fullStr The Impact of Oral Contraceptive Use on Selected Vitamins and Minerals in Women of Reproductive Age
title_full_unstemmed The Impact of Oral Contraceptive Use on Selected Vitamins and Minerals in Women of Reproductive Age
title_short The Impact of Oral Contraceptive Use on Selected Vitamins and Minerals in Women of Reproductive Age
title_sort impact of oral contraceptive use on selected vitamins and minerals in women of reproductive age
topic contraceptives
micronutrients
childbearing age
Gaza
url https://www.mdpi.com/2504-3900/88/1/1
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