What and Where Else: Hypervirulent Klebsiella pneumoniae With Pyogenic Liver Abscess and Disseminated Multifocal Osteomyelitis
Hypervirulent Klebsiella pneumoniae (hvKp), a pathotype of Klebsiella pneumoniae presents many clinical challenges. hvKp often causes disseminated, invasive disease in immunocompetent hosts. It is primarily associated with pyogenic liver abscesses, but also causes osteomyelitis, necrotizing fasciiti...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
American College of Physicians
2022-11-01
|
| Series: | Annals of Internal Medicine: Clinical Cases |
| Online Access: | https://www.acpjournals.org/doi/10.7326/aimcc.2022.0814 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849698873933561856 |
|---|---|
| author | Antonious Anis Madlena Nalbandian Chester Choi |
| author_facet | Antonious Anis Madlena Nalbandian Chester Choi |
| author_sort | Antonious Anis |
| collection | DOAJ |
| description | Hypervirulent Klebsiella pneumoniae (hvKp), a pathotype of Klebsiella pneumoniae presents many clinical challenges. hvKp often causes disseminated, invasive disease in immunocompetent hosts. It is primarily associated with pyogenic liver abscesses, but also causes osteomyelitis, necrotizing fasciitis, endophthalmitis, and meningitis. The diagnosis of hvKp is largely clinical because many laboratories lack the ability to test for the associated biomarkers. To emphasize the need to assess for disseminated invasive infection in such patients, we present a patient with hvKp who had bacteremic and tibial osteomyelitis, but also pyogenic liver abscess and multifocal osteomyelitis with a pathologic fracture. |
| format | Article |
| id | doaj-art-d925be405f0844bc8cf804444288af71 |
| institution | DOAJ |
| issn | 2767-7664 |
| language | English |
| publishDate | 2022-11-01 |
| publisher | American College of Physicians |
| record_format | Article |
| series | Annals of Internal Medicine: Clinical Cases |
| spelling | doaj-art-d925be405f0844bc8cf804444288af712025-08-20T03:18:46ZengAmerican College of PhysiciansAnnals of Internal Medicine: Clinical Cases2767-76642022-11-011910.7326/aimcc.2022.0814What and Where Else: Hypervirulent Klebsiella pneumoniae With Pyogenic Liver Abscess and Disseminated Multifocal OsteomyelitisAntonious Anis0Madlena Nalbandian1Chester Choi21Dignity Health St Mary Medical Center Long Beach, Long Beach, California3Dignity Health St. Bernardine Medical Center, Long Beach, California1Dignity Health St Mary Medical Center Long Beach, Long Beach, CaliforniaHypervirulent Klebsiella pneumoniae (hvKp), a pathotype of Klebsiella pneumoniae presents many clinical challenges. hvKp often causes disseminated, invasive disease in immunocompetent hosts. It is primarily associated with pyogenic liver abscesses, but also causes osteomyelitis, necrotizing fasciitis, endophthalmitis, and meningitis. The diagnosis of hvKp is largely clinical because many laboratories lack the ability to test for the associated biomarkers. To emphasize the need to assess for disseminated invasive infection in such patients, we present a patient with hvKp who had bacteremic and tibial osteomyelitis, but also pyogenic liver abscess and multifocal osteomyelitis with a pathologic fracture.https://www.acpjournals.org/doi/10.7326/aimcc.2022.0814 |
| spellingShingle | Antonious Anis Madlena Nalbandian Chester Choi What and Where Else: Hypervirulent Klebsiella pneumoniae With Pyogenic Liver Abscess and Disseminated Multifocal Osteomyelitis Annals of Internal Medicine: Clinical Cases |
| title | What and Where Else: Hypervirulent Klebsiella pneumoniae With Pyogenic Liver Abscess and Disseminated Multifocal Osteomyelitis |
| title_full | What and Where Else: Hypervirulent Klebsiella pneumoniae With Pyogenic Liver Abscess and Disseminated Multifocal Osteomyelitis |
| title_fullStr | What and Where Else: Hypervirulent Klebsiella pneumoniae With Pyogenic Liver Abscess and Disseminated Multifocal Osteomyelitis |
| title_full_unstemmed | What and Where Else: Hypervirulent Klebsiella pneumoniae With Pyogenic Liver Abscess and Disseminated Multifocal Osteomyelitis |
| title_short | What and Where Else: Hypervirulent Klebsiella pneumoniae With Pyogenic Liver Abscess and Disseminated Multifocal Osteomyelitis |
| title_sort | what and where else hypervirulent klebsiella pneumoniae with pyogenic liver abscess and disseminated multifocal osteomyelitis |
| url | https://www.acpjournals.org/doi/10.7326/aimcc.2022.0814 |
| work_keys_str_mv | AT antoniousanis whatandwhereelsehypervirulentklebsiellapneumoniaewithpyogenicliverabscessanddisseminatedmultifocalosteomyelitis AT madlenanalbandian whatandwhereelsehypervirulentklebsiellapneumoniaewithpyogenicliverabscessanddisseminatedmultifocalosteomyelitis AT chesterchoi whatandwhereelsehypervirulentklebsiellapneumoniaewithpyogenicliverabscessanddisseminatedmultifocalosteomyelitis |