NSAID-induced gastro-duodenal bleeding: risk of development and patient management

A.P. Rebrov, E.l. Koshkina, A.A. Antonyan, R.V. Lyakisheva NSAID-induced gastro-duodenal bleeding: risk of development and patient management. Retrospective analysis of gastro-duodenal bleeding (GDB) report forms was performed. Pts admitted to the department of internal diseases of Saratov regional...

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Main Authors: A P Rebrov, E I Kashkina, A A Antonyan, R V Lyakisheva
Format: Article
Language:Russian
Published: IMA PRESS LLC 2008-04-01
Series:Научно-практическая ревматология
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Online Access:https://rsp.mediar-press.net/rsp/article/view/564
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author A P Rebrov
E I Kashkina
A A Antonyan
R V Lyakisheva
author_facet A P Rebrov
E I Kashkina
A A Antonyan
R V Lyakisheva
author_sort A P Rebrov
collection DOAJ
description A.P. Rebrov, E.l. Koshkina, A.A. Antonyan, R.V. Lyakisheva NSAID-induced gastro-duodenal bleeding: risk of development and patient management. Retrospective analysis of gastro-duodenal bleeding (GDB) report forms was performed. Pts admitted to the department of internal diseases of Saratov regional clinical hospital from 1999 to 2004 were included. 354 cases of GDB were recorded ( 282 from 1999 to 2001 and 72 from 2002 to 2004). Cause ofbleeding, influence of NSAID administration on appearance and relapse ofbleeding, source ofbleeding and pt management were assessed. NSAJD administration was considered trigger factor of GDB in 24% in 1999-2001 and in 18% in 2002-2004. The results of the study show some tendency to decrease of NSAID- induced gastropathy frequency among causes of GDB. The main risk factors ofbleeding during NSAID treatment were age of more than 30 years, ulcer history, the first month of NSAID administration. GDB frequency did not depend on regularity of treatment and NSAID dosage.
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series Научно-практическая ревматология
spelling doaj-art-d91152121e2f4bb2b8ce810a241ac3ff2025-08-20T03:01:57ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922008-04-01462131510.14412/1995-4484-2008-426504NSAID-induced gastro-duodenal bleeding: risk of development and patient managementA P RebrovE I KashkinaA A AntonyanR V LyakishevaA.P. Rebrov, E.l. Koshkina, A.A. Antonyan, R.V. Lyakisheva NSAID-induced gastro-duodenal bleeding: risk of development and patient management. Retrospective analysis of gastro-duodenal bleeding (GDB) report forms was performed. Pts admitted to the department of internal diseases of Saratov regional clinical hospital from 1999 to 2004 were included. 354 cases of GDB were recorded ( 282 from 1999 to 2001 and 72 from 2002 to 2004). Cause ofbleeding, influence of NSAID administration on appearance and relapse ofbleeding, source ofbleeding and pt management were assessed. NSAJD administration was considered trigger factor of GDB in 24% in 1999-2001 and in 18% in 2002-2004. The results of the study show some tendency to decrease of NSAID- induced gastropathy frequency among causes of GDB. The main risk factors ofbleeding during NSAID treatment were age of more than 30 years, ulcer history, the first month of NSAID administration. GDB frequency did not depend on regularity of treatment and NSAID dosage.https://rsp.mediar-press.net/rsp/article/view/564gastro-duodenal bleedingnsaid-induced gastropathystomach ulcer
spellingShingle A P Rebrov
E I Kashkina
A A Antonyan
R V Lyakisheva
NSAID-induced gastro-duodenal bleeding: risk of development and patient management
Научно-практическая ревматология
gastro-duodenal bleeding
nsaid-induced gastropathy
stomach ulcer
title NSAID-induced gastro-duodenal bleeding: risk of development and patient management
title_full NSAID-induced gastro-duodenal bleeding: risk of development and patient management
title_fullStr NSAID-induced gastro-duodenal bleeding: risk of development and patient management
title_full_unstemmed NSAID-induced gastro-duodenal bleeding: risk of development and patient management
title_short NSAID-induced gastro-duodenal bleeding: risk of development and patient management
title_sort nsaid induced gastro duodenal bleeding risk of development and patient management
topic gastro-duodenal bleeding
nsaid-induced gastropathy
stomach ulcer
url https://rsp.mediar-press.net/rsp/article/view/564
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AT eikashkina nsaidinducedgastroduodenalbleedingriskofdevelopmentandpatientmanagement
AT aaantonyan nsaidinducedgastroduodenalbleedingriskofdevelopmentandpatientmanagement
AT rvlyakisheva nsaidinducedgastroduodenalbleedingriskofdevelopmentandpatientmanagement