Platelets express adaptor proteins of the extrinsic apoptosis pathway and can activate caspase-8.

Platelets express adaptor proteins of the extrinsic apoptosis pathway and can activate caspase-8.

<h4>Background</h4>Apoptotic pathways in platelets are important for their survival and function. Platelet apoptosis may be involved in the pathogenesis of immune thrombocytopenia (ITP), an autoimmune-mediated disease. In contrast to the intrinsic apoptosis pathway, not much is known abo...

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Main Authors: Nadine Goelz, Julia J M Eekels, Milica Pantic, Christoph T Kamber, Oliver Speer, Francesca D Franzoso, Markus Schmugge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0244848&type=printable
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