Establishing rabbit critical-size bone defects to evaluate the bone-regeneration potential of porous calcium phosphate ceramics

Establishing rabbit critical-size bone defects to evaluate the bone-regeneration potential of porous calcium phosphate ceramics

Critical-size bone defects (CSDs), which are those that do not self-repair in a given period, are essential for evaluating bone-regeneration strategies. We established CSDs models in the rabbit cranium and ulna, and the bone-regeneration capacities of porous calcium phosphate (CaP) ceramics were ass...

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Bibliographic Details
Main Authors: Wei Lei, Yan Wu, Hao Yuan, Ping He, Jingqi Wu, Jingrong Chen, Yuxiao Liu, Hongmei Zhang, Joost D. de Bruijn, Xuerong Xiang, Ping Ji, Huipin Yuan, Mingzheng Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
critical-size bone defect
bone regeneration
bone substitutes
calcium phosphate ceramic
submicron surface topography
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2024.1524133/full
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