High Glucose with Insulin Induces Cell Cycle Progression and Activation of Oncogenic Signaling of Bladder Epithelial Cells Cotreated with Metformin and Pioglitazone
Metformin and pioglitazone are two commonly prescribed oral hypoglycemic agents for diabetes. Recent evidence suggests that these drugs may contribute to bladder cancer. This study investigated molecular mechanism underlying effects of metformin and pioglitazone in bladder epithelial carcinogenesis...
Saved in:
Main Authors: | Daejin Kim, Byul-Nim Ahn, YeongSeok Kim, Dae Young Hur, Jae Wook Yang, Ga Bin Park, Jung Eun Jang, Eun Ju Lee, Min Jeong Kwon, Tae Nyun Kim, Mi Kyung Kim, Jeong Hyun Park, Byoung Doo Rhee, Soon Hee Lee |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2019-01-01
|
Series: | Journal of Diabetes Research |
Online Access: | http://dx.doi.org/10.1155/2019/2376512 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Metformin Attenuates Experimental Autoimmune Arthritis through Reciprocal Regulation of Th17/Treg Balance and Osteoclastogenesis
by: Hye-Jin Son, et al.
Published: (2014-01-01) -
Clinical Trial of Human Fetal Brain-Derived Neural Stem/Progenitor Cell Transplantation in Patients with Traumatic Cervical Spinal Cord Injury
by: Ji Cheol Shin, et al.
Published: (2015-01-01) -
Gut–brain axis and environmental factors in Parkinson’s disease: bidirectional link between disease onset and progression
by: Soo Jung Park, et al.
Published: (2025-12-01) -
Effect of Human Mesenchymal Stem Cells on Xenogeneic T and B Cells Isolated from Lupus-Prone MRL.Faslpr Mice
by: Hong Kyung Lee, et al.
Published: (2020-01-01) -
Nonislet Cell Tumor Hypoglycemia in a Patient with Adrenal Cortical Carcinoma
by: Se Won Kim, et al.
Published: (2016-01-01)