RIPK1 in necroptosis and recent progress in related pharmaceutics

RIPK1 in necroptosis and recent progress in related pharmaceutics

Necroptosis is a programmed form of cell death. Receptor-interacting serine/threonine protein kinase l (RIPK1) is a crucial protein kinase that regulates the necroptosis pathway. Increased expression of death receptor family ligands such as tumor necrosis factor (TNF) increases the susceptibility of...

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Bibliographic Details
Main Authors:	Kunhou Yao, Zhihao Shi, Fengya Zhao, Cong Tan, Yixin Zhang, Hao Fan, Yingzhe Wang, Xingwang Li, Jun Kong, Qun Wang, Dingxi Li
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-02-01
Series:	Frontiers in Immunology
Subjects:	RIPK1 necroptosis programmed cell death inflammation kinase domain pharmaceutics
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1480027/full
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