THE PREVALENCE OF NON-ALCOHOLIC FATTY LIVER DISEASE IN OUTPATIENTS IN THE FAR EAST FEDERAL DISTRICT
The rapidly growing incidence of obesity and diabetes mellitus, especially in developed countries, stimulates medical experts to closely study the epidemiology of non-alcoholic fatty liver disease (NAFLD). According to the published results of the epidemiological study DIREG 2, the prevalence of NAF...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
IRBIS LLC
2017-05-01
|
| Series: | Фармакоэкономика |
| Subjects: | |
| Online Access: | https://www.pharmacoeconomics.ru/jour/article/view/183 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849249717301542912 |
|---|---|
| author | V. A. Nevzorova M. V. Mokshina T. A. Brodskaya D. A. Vasil’chenkov D. V. Blinov T. I. Ushakova |
| author_facet | V. A. Nevzorova M. V. Mokshina T. A. Brodskaya D. A. Vasil’chenkov D. V. Blinov T. I. Ushakova |
| author_sort | V. A. Nevzorova |
| collection | DOAJ |
| description | The rapidly growing incidence of obesity and diabetes mellitus, especially in developed countries, stimulates medical experts to closely study the epidemiology of non-alcoholic fatty liver disease (NAFLD). According to the published results of the epidemiological study DIREG 2, the prevalence of NAFLD in outpatients inRussiaincreased over the period from 2007 to 2015 and amounted to 37.3%. In the present report, the population of patients with NAFLD in the Far East Federal District (FEFD) was studied as part of the multicentre epidemiological study DIREG 2.The aim. To analyze the data on FEFD obtained in the DIREG 2 study and compare those with the DIREG 2 data on the entireRussia.Materials and Methods. The prospective disease registry study: epidemiological, observational, cross-sectional, multicentre study on the prevalence of NAFLD in outpatients. The total number of participating patients in FEFD was 2500, including 900 males and 1600 females. Epidemiological data were collected within two routine patient visits to the participating research centers.Results. The major result of this study is that the prevalence of NAFLD in FEFD was significantly lower than that in the entireRussia (21.4% vs 37.3%). Although the rank distribution of the concomitant diseases in FEFD patients was comparable to that in the across-Russia population, the prevalence of metabolic syndrome, menopausal syndrome and hypertriglyceridemia was significantly higher in the FEFD population.Conclusion. Despite the lower prevalence of NAFLD there is a significantly higher prevalence of disorders associated with NAFLD in the FEFD patients as compared with the acrossRussian patients from DIREG2. A set of measures preventing these risk factors from converting into full-scale disease is needed. |
| format | Article |
| id | doaj-art-d8ec47d83e514edba8290c1aad009679 |
| institution | Kabale University |
| issn | 2070-4909 2070-4933 |
| language | Russian |
| publishDate | 2017-05-01 |
| publisher | IRBIS LLC |
| record_format | Article |
| series | Фармакоэкономика |
| spelling | doaj-art-d8ec47d83e514edba8290c1aad0096792025-08-20T03:57:30ZrusIRBIS LLCФармакоэкономика2070-49092070-49332017-05-01101576510.17749/2070-4909.2017.10.1.057-065165THE PREVALENCE OF NON-ALCOHOLIC FATTY LIVER DISEASE IN OUTPATIENTS IN THE FAR EAST FEDERAL DISTRICTV. A. Nevzorova0M. V. Mokshina1T. A. Brodskaya2D. A. Vasil’chenkov3D. V. Blinov4T. I. Ushakova5Pacific State Medical UniversityPacific State Medical UniversityPacific State Medical UniversityMoscow State University of Medicine and Dentistry named A. I. EvdokimovPirogov Russian National Research Medical UniversityCM Practice LLCThe rapidly growing incidence of obesity and diabetes mellitus, especially in developed countries, stimulates medical experts to closely study the epidemiology of non-alcoholic fatty liver disease (NAFLD). According to the published results of the epidemiological study DIREG 2, the prevalence of NAFLD in outpatients inRussiaincreased over the period from 2007 to 2015 and amounted to 37.3%. In the present report, the population of patients with NAFLD in the Far East Federal District (FEFD) was studied as part of the multicentre epidemiological study DIREG 2.The aim. To analyze the data on FEFD obtained in the DIREG 2 study and compare those with the DIREG 2 data on the entireRussia.Materials and Methods. The prospective disease registry study: epidemiological, observational, cross-sectional, multicentre study on the prevalence of NAFLD in outpatients. The total number of participating patients in FEFD was 2500, including 900 males and 1600 females. Epidemiological data were collected within two routine patient visits to the participating research centers.Results. The major result of this study is that the prevalence of NAFLD in FEFD was significantly lower than that in the entireRussia (21.4% vs 37.3%). Although the rank distribution of the concomitant diseases in FEFD patients was comparable to that in the across-Russia population, the prevalence of metabolic syndrome, menopausal syndrome and hypertriglyceridemia was significantly higher in the FEFD population.Conclusion. Despite the lower prevalence of NAFLD there is a significantly higher prevalence of disorders associated with NAFLD in the FEFD patients as compared with the acrossRussian patients from DIREG2. A set of measures preventing these risk factors from converting into full-scale disease is needed.https://www.pharmacoeconomics.ru/jour/article/view/183direg 2epidemiologynafldnon-alcoholic fatty liver diseasenashnon-alcoholic steatohepatitisprevalencevladivostokfar east federal districtfefd |
| spellingShingle | V. A. Nevzorova M. V. Mokshina T. A. Brodskaya D. A. Vasil’chenkov D. V. Blinov T. I. Ushakova THE PREVALENCE OF NON-ALCOHOLIC FATTY LIVER DISEASE IN OUTPATIENTS IN THE FAR EAST FEDERAL DISTRICT Фармакоэкономика direg 2 epidemiology nafld non-alcoholic fatty liver disease nash non-alcoholic steatohepatitis prevalence vladivostok far east federal district fefd |
| title | THE PREVALENCE OF NON-ALCOHOLIC FATTY LIVER DISEASE IN OUTPATIENTS IN THE FAR EAST FEDERAL DISTRICT |
| title_full | THE PREVALENCE OF NON-ALCOHOLIC FATTY LIVER DISEASE IN OUTPATIENTS IN THE FAR EAST FEDERAL DISTRICT |
| title_fullStr | THE PREVALENCE OF NON-ALCOHOLIC FATTY LIVER DISEASE IN OUTPATIENTS IN THE FAR EAST FEDERAL DISTRICT |
| title_full_unstemmed | THE PREVALENCE OF NON-ALCOHOLIC FATTY LIVER DISEASE IN OUTPATIENTS IN THE FAR EAST FEDERAL DISTRICT |
| title_short | THE PREVALENCE OF NON-ALCOHOLIC FATTY LIVER DISEASE IN OUTPATIENTS IN THE FAR EAST FEDERAL DISTRICT |
| title_sort | prevalence of non alcoholic fatty liver disease in outpatients in the far east federal district |
| topic | direg 2 epidemiology nafld non-alcoholic fatty liver disease nash non-alcoholic steatohepatitis prevalence vladivostok far east federal district fefd |
| url | https://www.pharmacoeconomics.ru/jour/article/view/183 |
| work_keys_str_mv | AT vanevzorova theprevalenceofnonalcoholicfattyliverdiseaseinoutpatientsinthefareastfederaldistrict AT mvmokshina theprevalenceofnonalcoholicfattyliverdiseaseinoutpatientsinthefareastfederaldistrict AT tabrodskaya theprevalenceofnonalcoholicfattyliverdiseaseinoutpatientsinthefareastfederaldistrict AT davasilchenkov theprevalenceofnonalcoholicfattyliverdiseaseinoutpatientsinthefareastfederaldistrict AT dvblinov theprevalenceofnonalcoholicfattyliverdiseaseinoutpatientsinthefareastfederaldistrict AT tiushakova theprevalenceofnonalcoholicfattyliverdiseaseinoutpatientsinthefareastfederaldistrict AT vanevzorova prevalenceofnonalcoholicfattyliverdiseaseinoutpatientsinthefareastfederaldistrict AT mvmokshina prevalenceofnonalcoholicfattyliverdiseaseinoutpatientsinthefareastfederaldistrict AT tabrodskaya prevalenceofnonalcoholicfattyliverdiseaseinoutpatientsinthefareastfederaldistrict AT davasilchenkov prevalenceofnonalcoholicfattyliverdiseaseinoutpatientsinthefareastfederaldistrict AT dvblinov prevalenceofnonalcoholicfattyliverdiseaseinoutpatientsinthefareastfederaldistrict AT tiushakova prevalenceofnonalcoholicfattyliverdiseaseinoutpatientsinthefareastfederaldistrict |