Study of quality of life in patients with seborrheic keratosis using different treatment regimens
Objective of this work is to evaluate the effect of a new topical treatment scheme for seborrheic keratosis on the quality of life in comparison with invasive electrocoagulation technique in terms of secondary changes in the skin (dyschromia, scarring). Materials and methods. 90 patients with seb...
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Zaporizhzhia State Medical and Pharmaceutical University
2022-06-01
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| Series: | Сучасні медичні технології |
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| Online Access: | https://zmapo-journal.com/index.php/journal/article/view/221 |
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| author | G. I. Makurina L. O. Cherneda |
| author_facet | G. I. Makurina L. O. Cherneda |
| author_sort | G. I. Makurina |
| collection | DOAJ |
| description | Objective of this work is to evaluate the effect of a new topical treatment scheme for seborrheic keratosis on the quality of life in comparison with invasive electrocoagulation technique in terms of secondary changes in the skin (dyschromia, scarring).
Materials and methods. 90 patients with seborrheic keratoses (77 females (85.6%), 13 males (14.4%)) were examined at the "University Clinic" and the Department of Dermatovenerology and Cosmetology with the Course of Aesthetic Medicine of FPE of ZSMU. Clinical, dermatoscopic, ultrasound, and pathomorphological examinations were performed for diagnostic purposes. The patients were randomly allocated into 2 groups. Local therapy was recommended as treatment for the first group (n=60). Patients in the second group (n=30) were prescribed electrocoagulation to remove neoplasms. Quality of life was assessed using the standardized DLQI index. The degree of discomfort with the application of a 30% hydrogen peroxide solution was assessed using a visual analog scale.
Results. Only 13 patients (21,66%) in Group I had secondary skin changes in the form of hypopigmentation. At the same time 26 (86,66%) patients of Group II had an undesirable result after removal in the form of scar changes. Assessment of quality of life also indicates a significant difference when comparing topical and invasive treatment. According to the questionnaire results, patients in the main group had a score of 5 (4;6), whereas in the case of electrocoagulation removal the score was 7 (6;9) (U=373.5; p=0,000005).
Conclusions. The use of topical agents in the treatment of seborrheic keratosis demonstrates effective efficacy in the extent of skin clearing of these neoplasms. |
| format | Article |
| id | doaj-art-d8e648fcb3874fcaa59b42c86b5d614c |
| institution | Kabale University |
| issn | 2072-9367 |
| language | English |
| publishDate | 2022-06-01 |
| publisher | Zaporizhzhia State Medical and Pharmaceutical University |
| record_format | Article |
| series | Сучасні медичні технології |
| spelling | doaj-art-d8e648fcb3874fcaa59b42c86b5d614c2025-01-02T15:34:36ZengZaporizhzhia State Medical and Pharmaceutical UniversityСучасні медичні технології2072-93672022-06-012(53)556010.34287/MMT.2(53).2022.11221Study of quality of life in patients with seborrheic keratosis using different treatment regimensG. I. Makurina0L. O. Cherneda1Zaporizhizhia State Medical University, Zaporizhzhia, UkraineZaporizhizhia State Medical University, Zaporizhzhia, UkraineObjective of this work is to evaluate the effect of a new topical treatment scheme for seborrheic keratosis on the quality of life in comparison with invasive electrocoagulation technique in terms of secondary changes in the skin (dyschromia, scarring). Materials and methods. 90 patients with seborrheic keratoses (77 females (85.6%), 13 males (14.4%)) were examined at the "University Clinic" and the Department of Dermatovenerology and Cosmetology with the Course of Aesthetic Medicine of FPE of ZSMU. Clinical, dermatoscopic, ultrasound, and pathomorphological examinations were performed for diagnostic purposes. The patients were randomly allocated into 2 groups. Local therapy was recommended as treatment for the first group (n=60). Patients in the second group (n=30) were prescribed electrocoagulation to remove neoplasms. Quality of life was assessed using the standardized DLQI index. The degree of discomfort with the application of a 30% hydrogen peroxide solution was assessed using a visual analog scale. Results. Only 13 patients (21,66%) in Group I had secondary skin changes in the form of hypopigmentation. At the same time 26 (86,66%) patients of Group II had an undesirable result after removal in the form of scar changes. Assessment of quality of life also indicates a significant difference when comparing topical and invasive treatment. According to the questionnaire results, patients in the main group had a score of 5 (4;6), whereas in the case of electrocoagulation removal the score was 7 (6;9) (U=373.5; p=0,000005). Conclusions. The use of topical agents in the treatment of seborrheic keratosis demonstrates effective efficacy in the extent of skin clearing of these neoplasms.https://zmapo-journal.com/index.php/journal/article/view/221seborrheic keratosisdermatological quality of lifedyschromiascarringtopical oxidant |
| spellingShingle | G. I. Makurina L. O. Cherneda Study of quality of life in patients with seborrheic keratosis using different treatment regimens Сучасні медичні технології seborrheic keratosis dermatological quality of life dyschromia scarring topical oxidant |
| title | Study of quality of life in patients with seborrheic keratosis using different treatment regimens |
| title_full | Study of quality of life in patients with seborrheic keratosis using different treatment regimens |
| title_fullStr | Study of quality of life in patients with seborrheic keratosis using different treatment regimens |
| title_full_unstemmed | Study of quality of life in patients with seborrheic keratosis using different treatment regimens |
| title_short | Study of quality of life in patients with seborrheic keratosis using different treatment regimens |
| title_sort | study of quality of life in patients with seborrheic keratosis using different treatment regimens |
| topic | seborrheic keratosis dermatological quality of life dyschromia scarring topical oxidant |
| url | https://zmapo-journal.com/index.php/journal/article/view/221 |
| work_keys_str_mv | AT gimakurina studyofqualityoflifeinpatientswithseborrheickeratosisusingdifferenttreatmentregimens AT locherneda studyofqualityoflifeinpatientswithseborrheickeratosisusingdifferenttreatmentregimens |