A study to evaluate the lipid profile of patients presented with atrial fibrillation in a tertiary care center
Background: Atrial fibrillation (AF) significantly raises the risk of ischemic stroke, heart failure, cognitive decline, and cardiovascular death. In view of the substantial economic and healthcare challenges posed by AF, it is crucial to identify risk factors and develop effective prevention strate...
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Manipal College of Medical Sciences, Pokhara
2025-08-01
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| Series: | Asian Journal of Medical Sciences |
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| Online Access: | https://ajmsjournal.info/index.php/AJMS/article/view/4641 |
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| author | Nikita Kumari Sandip Sarkar Lipika Adhikari Abhijit Das Purnendu Dash Samridhi Yasha |
| author_facet | Nikita Kumari Sandip Sarkar Lipika Adhikari Abhijit Das Purnendu Dash Samridhi Yasha |
| author_sort | Nikita Kumari |
| collection | DOAJ |
| description | Background: Atrial fibrillation (AF) significantly raises the risk of ischemic stroke, heart failure, cognitive decline, and cardiovascular death. In view of the substantial economic and healthcare challenges posed by AF, it is crucial to identify risk factors and develop effective prevention strategies. Several studies published in different times showed inconsistent results regarding its relation with dyslipidemia.
Aims and Objectives: The aims and objectives were to find out the relationship between different lipid levels total cholesterol (TC), triglyceride (TG), low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL), and AF.
Materials and Methods: A total of 83 patients attending the department of cardiology with nonvalvular AF were included in the study group.
Results: Coronary artery disease (CAD) with AF (28.9%) was the most common diagnosis, followed by heart failure with preserved ejection fraction (HFpEF) with AF (20.5%), lone AF (14.5%), hypertrophic cardiomyopathy (HCM) with AF (14.5%). The mean LDL levels were highest in patients with CAD (115.07±16.3 mg/dL) and HFpEF (113.11±12.99 mg/dL), whereas the mean TC levels were also elevated in these groups. The mean HDL level was lowest among patients with lone AF (29.4±5.6 mg/dL).
Conclusion: Elevated LDL and TC levels are more frequently observed in patients with CAD and HFpEF, whereas low HDL levels are linked to lone AF. In patients with cardiomyopathies and lone AF, LDL and TC values are in the lower range supporting the “cholesterol paradox”. |
| format | Article |
| id | doaj-art-d8e6356f140044c28ce24445a9acf4ed |
| institution | DOAJ |
| issn | 2467-9100 2091-0576 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Manipal College of Medical Sciences, Pokhara |
| record_format | Article |
| series | Asian Journal of Medical Sciences |
| spelling | doaj-art-d8e6356f140044c28ce24445a9acf4ed2025-08-20T03:16:28ZengManipal College of Medical Sciences, PokharaAsian Journal of Medical Sciences2467-91002091-05762025-08-011681015https://doi.org/10.71152/ajms.v16i8.4641A study to evaluate the lipid profile of patients presented with atrial fibrillation in a tertiary care centerNikita Kumari 0https://orcid.org/0009-0006-7784-2718Sandip Sarkar 1https://orcid.org/0000-0002-0621-024XLipika Adhikari 2https://orcid.org/0000-0002-3927-5197Abhijit Das 3https://orcid.org/0000-0003-3857-3341Purnendu Dash 4https://orcid.org/0009-0007-8276-9129Samridhi Yasha 5https://orcid.org/0009-0006-2594-8908Senior Resident, Department of Cardiology, RG Kar Medical College, Kolkata, West Bengal, India Assistant Professor, Department of Obstetrics and Gynaecology, RG Kar Medical College, Kolkata, West Bengal, India Associate Professor, Department of Cardiology, RG Kar Medical College, Kolkata, West Bengal, India Senior Resident, Department of Cardiology, RG Kar Medical College, Kolkata, West Bengal, India Postgraduate Resident, Department of Cardiology, RG Kar Medical College, Kolkata, West Bengal, India Postgraduate Resident, Department of Cardiology, RG Kar Medical College, Kolkata, West Bengal, India Background: Atrial fibrillation (AF) significantly raises the risk of ischemic stroke, heart failure, cognitive decline, and cardiovascular death. In view of the substantial economic and healthcare challenges posed by AF, it is crucial to identify risk factors and develop effective prevention strategies. Several studies published in different times showed inconsistent results regarding its relation with dyslipidemia. Aims and Objectives: The aims and objectives were to find out the relationship between different lipid levels total cholesterol (TC), triglyceride (TG), low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL), and AF. Materials and Methods: A total of 83 patients attending the department of cardiology with nonvalvular AF were included in the study group. Results: Coronary artery disease (CAD) with AF (28.9%) was the most common diagnosis, followed by heart failure with preserved ejection fraction (HFpEF) with AF (20.5%), lone AF (14.5%), hypertrophic cardiomyopathy (HCM) with AF (14.5%). The mean LDL levels were highest in patients with CAD (115.07±16.3 mg/dL) and HFpEF (113.11±12.99 mg/dL), whereas the mean TC levels were also elevated in these groups. The mean HDL level was lowest among patients with lone AF (29.4±5.6 mg/dL). Conclusion: Elevated LDL and TC levels are more frequently observed in patients with CAD and HFpEF, whereas low HDL levels are linked to lone AF. In patients with cardiomyopathies and lone AF, LDL and TC values are in the lower range supporting the “cholesterol paradox”.https://ajmsjournal.info/index.php/AJMS/article/view/4641lipid profile; atrial fibrillation; coronary artery disease; dilated cardiomyopathy; restrictive cardiomyopathy; hypertrophic cardiomyopathy; constrictive pericarditis |
| spellingShingle | Nikita Kumari Sandip Sarkar Lipika Adhikari Abhijit Das Purnendu Dash Samridhi Yasha A study to evaluate the lipid profile of patients presented with atrial fibrillation in a tertiary care center Asian Journal of Medical Sciences lipid profile; atrial fibrillation; coronary artery disease; dilated cardiomyopathy; restrictive cardiomyopathy; hypertrophic cardiomyopathy; constrictive pericarditis |
| title | A study to evaluate the lipid profile of patients presented with atrial fibrillation in a tertiary care center |
| title_full | A study to evaluate the lipid profile of patients presented with atrial fibrillation in a tertiary care center |
| title_fullStr | A study to evaluate the lipid profile of patients presented with atrial fibrillation in a tertiary care center |
| title_full_unstemmed | A study to evaluate the lipid profile of patients presented with atrial fibrillation in a tertiary care center |
| title_short | A study to evaluate the lipid profile of patients presented with atrial fibrillation in a tertiary care center |
| title_sort | study to evaluate the lipid profile of patients presented with atrial fibrillation in a tertiary care center |
| topic | lipid profile; atrial fibrillation; coronary artery disease; dilated cardiomyopathy; restrictive cardiomyopathy; hypertrophic cardiomyopathy; constrictive pericarditis |
| url | https://ajmsjournal.info/index.php/AJMS/article/view/4641 |
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